Naphthyloxyacetic Acid

Naphthyloxyacetic Acid

SCHEMBL120838

O=C(O)COc1cccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 1.00
ALDH1A1 P00352 4/20 1.00
HPGD P15428 3/20 1.00
TDP1 Q9NUW8 1/20 1.00
OGG1 O15527 1/20 0.66
TSHR P16473 1/20 0.62
SMN1; SMN2 Q16637 2/20 0.60
LMNA P02545 2/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
POLB P06746 1/20 0.58
GLA P06280 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
HTT P42858 2/20 0.57
MAPT P10636 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
HSD17B10 Q99714 1/20 0.57
DAPK1 P53355 1/20 0.56
PIM3 Q86V86 1/20 0.56
MRGPRX4 Q96LA9 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthyloxyacetic Acid SCHEMBL29364154 1.00 KDM4E (1.00) KDM4EALDH1A1HPGDTDP1OGG1
Naphthyloxyacetic Acid SCHEMBL6820182 0.98 KDM4E (0.96) KDM4EALDH1A1HPGDTDP1OGG1
Naphthyloxyacetic Acid SCHEMBL8441282 0.98 KDM4E (0.96) KDM4EALDH1A1HPGDTDP1OGG1
Naphthyloxyacetic Acid SCHEMBL15201763 0.98 KDM4E (0.96) KDM4EALDH1A1HPGDTDP1OGG1
Naphthyloxyacetic Acid SCHEMBL27718734 0.95 KDM4E (0.90) KDM4EALDH1A1HPGDTDP1OGG1
Naphthyloxyacetic Acid SCHEMBL9929467 0.92 KDM4E (0.84) KDM4EALDH1A1HPGDTDP1OGG1
Naphthyloxyacetic Acid SCHEMBL8920389 0.89 ALDH1A1 (0.79) KDM4EALDH1A1HPGDTDP1OGG1
Naphthyloxyacetic Acid SCHEMBL27658809 0.88 KDM4E (0.77) KDM4EALDH1A1HPGDTDP1OGG1
SCHEMBL27211583 0.87 KDM4E (0.77) KDM4EALDH1A1HPGDTDP1OGG1
SCHEMBL27876965 0.86 ALDH1A1 (0.76) KDM4EALDH1A1HPGDTDP1OGG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3734 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396745-B Method for dispersing up-conversion luminescence nano particles in medium-polarity solvent and preparation method of film material 浙江大学 2025-05-06 CN claimed
CN-119874549-A Preparation method and application of naproxen bis-urethane compound 四川施成收生态科技有限公司 2025-04-25 CN claimed
CN-115108905-B Method for producing (Z) -trifluoromethaneenol ester by copper-catalyzed regioselective olefination and trifluoromethylation of carboxylic acid 湖南大学 2025-04-08 CN claimed
CN-119769376-A Planting method for promoting nitrogen fixation efficiency of sugarcane by intercropping mung bean and soybean 广西壮族自治区农业科学院 2025-04-08 CN claimed
CN-119390761-A Self-assembled antibacterial short peptide based on aromatic group induction and application thereof 兰州大学 2025-02-07 CN claimed
CN-118479926-B Banana plant regulator composition, preparation method and application thereof, and banana plant regulator preparation 中锦集团(海南)有限公司 2025-01-14 CN claimed
CN-119138435-A Garden plant growth regulator composition and preparation method and application thereof 临沂市园林环卫保障服务中心 2024-12-17 CN claimed
CN-118479926-A Banana plant regulator composition, preparation method and application thereof, and banana plant regulator preparation 中锦集团(海南)有限公司 2024-08-13 CN claimed
US-20240138408-A1 COMPOSITION COMPRISING BENZYLAMINE ACARICIDE AND USE THEREOF SHANGDONG KANGIAO BIO-TECHNOLOGY CO., LTD (CN) 2024-05-02 US claimed
CN-117730694-A Seedling pressing propagation method for endangered tree species 保山市林草种子管理站 2024-03-22 CN claimed
EP-0657422-B1 Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists ONO PHARMACEUTICAL CO (JP) 1998-06-10 EP claimed
EP-0845451-A1 NAPHTHYLOXYACETIC ACID DERIVATIVES AND DRUGS COMPRISING THE SAME AS ACTIVE INGREDIENTS ONO PHARMACEUTICAL CO., LTD. (JP) 1998-06-03 EP claimed
US-5753700-A ANALGESICS; CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS ONO PHARMACEUTICAL CO., LTD. (JP) 1998-05-19 US claimed
US-5723493-A PROSTAGLANDIN DERIVATIVES ONO PHARMACEUTICAL CO., LTD. (JP) 1998-03-03 US claimed
WO-1997044476-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON, INC. (US) 1997-11-27 WO claimed
US-5624959-A INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS ONO PHARMACEUTICAL CO., LTD. (JP) 1997-04-29 US claimed
EP-0719760-A1 Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists ONO PHARMACEUTICAL CO., LTD. (JP) 1996-07-03 EP claimed
CN-1111612-A Naphthyloxyacetic acid derivatives ONO PHARMACEUTICAL CO (JP) 1995-11-15 CN claimed
EP-0657422-A1 Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists ONO PHARMACEUTICAL CO., LTD. (JP) 1995-06-14 EP claimed
US-4246040-A REACTING BASIC POLYALUMINUM SALT WITH AN ACID IN PRESENCE OF POWDER NIHONSHIKIZAI KOGYO CO., LTD. (JP) 1981-01-20 US claimed