Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | OGG1 | O15527 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 2/20 | 0.55 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067222 | 0.91 | KDM4E (0.70) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL9329851 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL9339934 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL28881020 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL30499047 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL4908724 | 0.87 | KDM4E (0.74) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| Naphthyloxyacetic Acid SCHEMBL120838 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| Naphthyloxyacetic Acid SCHEMBL29364154 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL27852221 | 0.87 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL1614613 | 0.85 | KDM4E (0.72) | KDM4EALDH1A1HPGDTDP1OGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12048306-B1 | 1,3-bis(naphthalen-1-yloxy)propan-2-one as an eco-friendly insecticidal agent against Spodoptera littoralis (boisd.) | King Faisal University (SA) | 2024-07-30 | — | — | US | claimed |
| US-12048306-B1 | 1,3-bis(naphthalen-1-yloxy)propan-2-one as an eco-friendly insecticidal agent against Spodoptera littoralis (boisd.) | King Faisal University (SA) | 2024-07-30 | — | — | US | disclosed |
| US-12048306-B1 | 1,3-bis(naphthalen-1-yloxy)propan-2-one as an eco-friendly insecticidal agent against Spodoptera littoralis (boisd.) | King Faisal University (SA) | 2024-07-30 | — | — | US | disclosed |
| US-12048306-B1 | 1,3-bis(naphthalen-1-yloxy)propan-2-one as an eco-friendly insecticidal agent against Spodoptera littoralis (boisd.) | King Faisal University (SA) | 2024-07-30 | — | — | US | disclosed |
| US-11974570-B1 | 1,3-bis(naphthalen-1-yloxy)propan-2-one an eco-friendly insecticidal agent against Spodoptera littoralis (Boisd.) | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
| US-11974570-B1 | 1,3-bis(naphthalen-1-yloxy)propan-2-one an eco-friendly insecticidal agent against Spodoptera littoralis (Boisd.) | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
| US-11974570-B1 | 1,3-bis(naphthalen-1-yloxy)propan-2-one an eco-friendly insecticidal agent against Spodoptera littoralis (Boisd.) | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12048306-B1 | 1,3-bis(naphthalen-1-yloxy)propan-2-one as an eco-friendly insecticidal agent against Spodoptera littoralis (boisd.) | BAK1, PIR, DDT | KDM4E 1635/4885ALDH1A1 754/4885HPGD 194/4885 |
| US-11974570-B1 | 1,3-bis(naphthalen-1-yloxy)propan-2-one an eco-friendly insecticidal agent against Spodoptera littoralis (Boisd.) | BAK1, PIR, BCL2 | KDM4E 1505/4885ALDH1A1 854/4885HPGD 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.