Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071814 | 0.79 | AKT1 (0.38) | MAPTKMT2AMEN1LMNACYP3A4 | |
| SCHEMBL1071816 | 0.79 | AKT1 (0.38) | MAPTKMT2AMEN1LMNACYP3A4 | |
| SCHEMBL18637029 | 0.77 | MAPT (0.48) | MAPTESR1KMT2AHSD17B10MEN1 | |
| SCHEMBL15189004 | 0.77 | CA2 (0.44) | MAPTLMNACA12CA1CA2 | |
| SCHEMBL17214449 | 0.76 | CYP1A2 (0.41) | KMT2AHSD17B10MEN1LMNACYP1A2 | |
| SCHEMBL12453517 | 0.76 | F3 (0.59) | MAPTESR1KMT2AMEN1LMNA | |
| SCHEMBL14340575 | 0.76 | MAPT (0.46) | MAPTESR1KMT2AHSD17B10MEN1 | |
| SCHEMBL23786844 | 0.75 | CA1 (0.42) | CA1CA2 | |
| SCHEMBL8377034 | 0.75 | CYP1A1 (0.45) | CYP1A2P4HBPTGS1PTGS2NQO2 | |
| Bicarbonate SCHEMBL11378162 | 0.74 | AKT1 (0.43) | MAPTKMT2AMEN1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2495323-A1 | MODIFIED DOUBLE-STRANDED POLYNUCLEOTIDE | Daiichi Sankyo Company, Limited (JP) | 2012-09-05 | — | — | EP | disclosed |