SCHEMBL12088488

SCHEMBL12088488

c1ccc(-c2cccc3c2oc2c(-n4c5ccccc5c5ccc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)cc54)cccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PRKDC P78527 6/20 0.34
ALDH1A1 P00352 5/20 0.33
PIK3CD O00329 2/20 0.33
PIK3CA P42336 2/20 0.33
PIK3CB P42338 2/20 0.33
PIK3CG P48736 2/20 0.33
BRD4 O60885 2/20 0.33
BRD2 P25440 2/20 0.33
BRD3 Q15059 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
PDE2A O00408 1/20 0.33
PIK3C2A O00443 1/20 0.33
PIK3R2 O00459 1/20 0.33
PIK3C2B O00750 1/20 0.33
PDE5A O76074 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15780918 0.97 KDM4E (0.43) KDM4EATML3MBTL1PRKDCALDH1A1
SCHEMBL10331651 0.97 KDM4E (0.43) KDM4EATML3MBTL1PRKDCALDH1A1
SCHEMBL5028253 0.92 KDM4E (0.45) KDM4EATML3MBTL1PRKDCALDH1A1
SCHEMBL22672184 0.92 KDM4E (0.35) KDM4EATML3MBTL1PRKDCPIK3CD
SCHEMBL16441443 0.90 KDM4E (0.34) KDM4EATML3MBTL1PRKDCALOX5
SCHEMBL23072320 0.90 KDM4E (0.38) KDM4EATML3MBTL1PRKDCALDH1A1
SCHEMBL15988940 0.90 KDM4E (0.47) KDM4EATML3MBTL1PRKDCALDH1A1
SCHEMBL10165773 0.90 KDM4E (0.47) KDM4EATML3MBTL1PRKDCALDH1A1
SCHEMBL10165765 0.88 KDM4E (0.49) KDM4EATML3MBTL1PRKDCALDH1A1
SCHEMBL10165770 0.88 KDM4E (0.49) KDM4EATML3MBTL1PRKDCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49237-E1 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2022-10-04 US disclosed
US-10230057-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2019-03-12 US disclosed
US-20180047917-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2018-02-15 US disclosed
US-20180047917-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2018-02-15 US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 US disclosed
US-9818958-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2017-11-14 US disclosed
US-9818958-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2017-11-14 US disclosed
US-20160240795-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-08-18 US disclosed
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-9373802-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2016-06-21 US disclosed
US-20140312331-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed
US-20140312331-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed
US-20140306207-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-16 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed
US-8803134-B2 Biscarbazole derivatives and organic electroluminescence IDEMITSU KOSAN CO., LTD. (JP) 2014-08-12 US disclosed
US-8803134-B2 Biscarbazole derivatives and organic electroluminescence IDEMITSU KOSAN CO., LTD. (JP) 2014-08-12 US disclosed
US-20120223295-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2012-09-06 US disclosed
US-20120223295-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2012-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180047917-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME EED, GABRE, EML4 KDM4E 312/4885ATM 3431/4885L3MBTL1 94/4885
US-20120223295-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE EED, GABRE, EML4 KDM4E 418/4885ATM 3559/4885L3MBTL1 116/4885
US-10230057-B2 Biscarbazole derivatives and organic electroluminescence device employing the same EED, GABRE, EML4 KDM4E 312/4885ATM 3431/4885L3MBTL1 94/4885
US-20140312331-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE EED, GABRE, EML4 KDM4E 418/4885ATM 3559/4885L3MBTL1 116/4885
US-20160240795-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME EED, GABRE, EML4 KDM4E 312/4885ATM 3431/4885L3MBTL1 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.