Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10271492 | 0.87 | HASPIN (0.46) | KDM4CHTR3ADYRK1AMAOAALDH1A1 | |
| SCHEMBL12090340 | 0.82 | DYRK1A (0.48) | KDM4CHTR3ADYRK1AALDH1A1HTT | |
| SCHEMBL20520453 | 0.79 | PDGFRA (0.41) | ALDH1A1 | |
| SCHEMBL30258317 | 0.79 | PDGFRA (0.41) | ALDH1A1 | |
| SCHEMBL12090307 | 0.79 | KDM4C (0.42) | KDM4CHTR3ADYRK1AALDH1A1KAT2B | |
| SCHEMBL12347982 | 0.78 | ADORA2A (0.55) | KDM4CHTR3ADYRK1AMAOAALDH1A1 | |
| SCHEMBL23530187 | 0.77 | KDM4C (0.43) | KDM4CHTR3ADYRK1AMAOAALDH1A1 | |
| SCHEMBL29550150 | 0.77 | KDM4C (0.43) | KDM4CHTR3ADYRK1AMAOAALDH1A1 | |
| SCHEMBL13899522 | 0.77 | KDR (0.59) | KDM4CHTR3ADYRK1AMAOAALDH1A1 | |
| SCHEMBL15792236 | 0.77 | KDM4C (0.43) | KDM4CHTR3ADYRK1AMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120225909-A1 | INDAZOLE ANALOG | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225909-A1 | INDAZOLE ANALOG | ADRB3, ADRB1, ADRB2 | KDM4C 4312/4885HTR3A 13/4885DYRK1A 1380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.