Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 4/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13089473 | 1.00 | THRB (0.53) | THRBTSHRALDH1A1CYP3A4F2 | |
| SCHEMBL13089464 | 1.00 | THRB (0.53) | THRBTSHRALDH1A1CYP3A4F2 | |
| SCHEMBL17279031 | 1.00 | THRB (0.53) | THRBTSHRALDH1A1CYP3A4F2 | |
| SCHEMBL19958229 | 0.96 | THRB (0.50) | THRBTSHRALDH1A1CYP3A4F2 | |
| SCHEMBL19844482 | 0.96 | THRB (0.50) | THRBTSHRALDH1A1CYP3A4F2 | |
| SCHEMBL12087298 | 0.95 | THRB (0.52) | THRBTSHRALDH1A1CYP3A4F2 | |
| SCHEMBL1071618 | 0.94 | THRB (0.64) | THRBTSHRALDH1A1CYP3A4F2 | |
| SCHEMBL22451086 | 0.94 | THRB (0.64) | THRBTSHRALDH1A1CYP3A4F2 | |
| SCHEMBL1073240 | 0.94 | THRB (0.64) | THRBTSHRALDH1A1CYP3A4F2 | |
| SCHEMBL13089465 | 0.94 | THRB (0.64) | THRBTSHRALDH1A1CYP3A4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303926-A1 | LIQUID CRYSTAL COMPOSITION, LIGHT ABSORPTION ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2023-09-28 | — | — | US | disclosed |
| EP-4039776-A2 | POLYMERISABLE LC MATERIAL AND POLYMER FILM | Merck Patent GmbH (DE) | 2022-08-10 | — | — | EP | disclosed |
| US-20220162505-A1 | Polymerizable LC Material and Polymer Film | MERCK PATENT GMBH (DE) | 2022-05-26 | — | — | US | disclosed |
| US-11248171-B2 | Polymerisable LC medium and polymer film with flat optical dispersion | MERCK PATENT GMBH (DE) | 2022-02-15 | — | — | US | disclosed |
| EP-3548586-B1 | POLYMERISABLE LC MEDIUM AND POLYMER FILM WITH FLAT OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2020-09-23 | — | — | EP | disclosed |
| US-10435628-B2 | Polymerisable LC medium and polymer film with negative optical dispersion | MERCK PATENT GMBH (DE) | 2019-10-08 | — | — | US | disclosed |
| US-10023743-B2 | Dichroic pigment compounds and compositions containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-07-17 | — | — | US | disclosed |
| US-10005960-B2 | Composition and polarizing film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20180037739-A1 | COMPOUND AND COMPOSITION CONTAINING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-08 | — | — | US | disclosed |
| US-20180030354-A1 | COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-01 | — | — | US | disclosed |
| CN-104803846-A | Method for the preparation of bis[4-(6-acryloyloxy-hexyl)-phenyl]cyclohexane-1,4-dicarboxylate | MERCK PATENT GMBH | 2015-07-29 | — | — | CN | disclosed |
| EP-2494004-B1 | POLYMERISABLE LC MATERIAL AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2013-09-25 | — | — | EP | disclosed |
| US-8470198-B2 | Mesogenic compounds comprising discotic and calamitic groups | MERCK PATENT GMBH (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8470198-B2 | Mesogenic compounds comprising discotic and calamitic groups | MERCK PATENT GMBH (DE) | 2013-06-25 | — | — | US | disclosed |
| US-20120224245-A1 | POLYMERISABLE LC MATERIAL AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | Merck Patent Gesellschaft mit bescrankter Haftung (DE) | 2012-09-06 | — | — | US | disclosed |
| US-20120224245-A1 | POLYMERISABLE LC MATERIAL AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | Merck Patent Gesellschaft mit bescrankter Haftung (DE) | 2012-09-06 | — | — | US | disclosed |
| US-20110147659-A1 | MESOGENIC COMPOUNDS COMPRISING DISCOTIC AND CALAMITIC GROUPS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20110147659-A1 | MESOGENIC COMPOUNDS COMPRISING DISCOTIC AND CALAMITIC GROUPS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-06-23 | — | — | US | disclosed |
| WO-2011050896-A1 | POLYMERISABLE LC MATERIAL AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2011-05-05 | — | — | WO | disclosed |
| WO-2010020312-A1 | MESOGENIC COMPOUNDS COMPRISING DISCOTIC AND CALAMITIC GROUPS | MERCK PATENT GMBH (DE) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110147659-A1 | MESOGENIC COMPOUNDS COMPRISING DISCOTIC AND CALAMITIC GROUPS | CALD1, DIAPH1, CALR | THRB 4767/4885TSHR 4625/4885ALDH1A1 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.