Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | VKORC1 | Q9BQB6 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354341 | 0.79 | KDM4E (0.55) | CA12CA9VKORC1CYP2C9KDM4E | |
| SCHEMBL12747979 | 0.75 | KDM4E (0.62) | CA12CA9VKORC1CYP2C9KDM4E | |
| SCHEMBL3778823 | 0.74 | ALDH1A1 (0.51) | CA12CA9VKORC1CYP2C9KDM4E | |
| SCHEMBL15514111 | 0.74 | ALDH1A1 (0.51) | CA12CA9VKORC1CYP2C9KDM4E | |
| SCHEMBL7351830 | 0.73 | ALDH1A1 (0.50) | CA12CA9VKORC1CYP2C9KDM4E | |
| SCHEMBL9286035 | 0.73 | NQO1 (0.53) | CA12CA9VKORC1CYP2C9KDM4E | |
| SCHEMBL1649890 | 0.72 | NQO1 (0.50) | CA12CA9VKORC1CYP2C9KDM4E | |
| SCHEMBL5103338 | 0.72 | NQO1 (0.52) | CA12CA9VKORC1CYP2C9KDM4E | |
| SCHEMBL7362388 | 0.70 | CA12 (0.48) | CA12CA9VKORC1CYP2C9KDM4E | |
| SCHEMBL6890789 | 0.70 | CYP2C9 (0.52) | CA12CA9VKORC1CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120226054-A1 | MULTIPLE STATIONARY PHASE MATRIX AND USES THEREOF | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2012-09-06 | — | — | US | disclosed |