Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | VKORC1 | Q9BQB6 | 3/20 | 0.46 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15514111 | 0.80 | ALDH1A1 (0.51) | CYP2C9CA12CA9ALDH1A1KDM4E | |
| SCHEMBL3778823 | 0.80 | ALDH1A1 (0.51) | CYP2C9CA12CA9ALDH1A1KDM4E | |
| SCHEMBL7351830 | 0.79 | ALDH1A1 (0.50) | CYP2C9NR1I2NR3C1ADRA1AKCNH2 | |
| SCHEMBL3048772 | 0.76 | ALDH1A1 (0.46) | CYP2C9CA12CA9ALDH1A1KDM4E | |
| SCHEMBL2358729 | 0.74 | LMNA (0.48) | CYP2C9CA12CA9ALDH1A1KDM4E | |
| SCHEMBL7354341 | 0.73 | KDM4E (0.55) | CYP2C9CA12CA9ALDH1A1KDM4E | |
| SCHEMBL9286035 | 0.72 | NQO1 (0.53) | CYP2C9CA12CA9ALDH1A1KDM4E | |
| SCHEMBL1649890 | 0.72 | NQO1 (0.50) | CYP2C9CA12CA9ALDH1A1KDM4E | |
| SCHEMBL5103338 | 0.71 | NQO1 (0.52) | CYP2C9CA12CA9ALDH1A1KDM4E | |
| SCHEMBL12091846 | 0.70 | CA12 (0.49) | CYP2C9CA12CA9ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040084867-A1 | Individualization of therapy with anticoagulants | XANTHUS LIFE SCIENCES, INC. | 2004-05-06 | — | — | US | disclosed |
| WO-2004003550-A2 | INDIVIDUALIZATION OF THERAPY WITH ANTICOAGULANTS | XANTHUS LIFE SCIENCES, INC. (US) | 2004-01-08 | — | — | WO | disclosed |