SCHEMBL12094756

SCHEMBL12094756

CCCC[C@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 8/20 0.56
▸ NPY1R P25929 3/20 0.53
▸ NPY2R P49146 3/20 0.53
▸ NPY4R P50391 3/20 0.53
▸ GHSR Q92847 1/20 0.53
▸ MMP2 P08253 1/20 0.52
▸ MMP9 P14780 1/20 0.52
▸ MMP8 P22894 1/20 0.52
▸ MMP14 P50281 1/20 0.52
▸ CCKAR P32238 1/20 0.52
▸ OPRD1 P41143 1/20 0.52
▸ KISS1R Q969F8 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12094757 0.94 MC4R (0.58) CCKBRKISS1R
SCHEMBL30418415 0.94 MC4R (0.58) CCKBRKISS1R
SCHEMBL12094755 0.94 MC4R (0.58) CCKBRKISS1R
SCHEMBL12094801 0.94 MC4R (0.58) CCKBRKISS1R
SCHEMBL12094764 0.94 MC4R (0.58) CCKBRKISS1R
SCHEMBL12094797 0.94 MC4R (0.58) CCKBRKISS1R
SCHEMBL18556749 0.94 CCKBR (0.61) CCKBRCCKAROPRD1KISS1R
SCHEMBL18556702 0.94 CCKBR (0.61) CCKBRCCKAROPRD1KISS1R
SCHEMBL18891478 0.90 MC4R (0.59) CCKBRCCKAROPRD1KISS1R
SCHEMBL16677035 0.90 MC4R (0.59) CCKBRCCKAROPRD1KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170145056-A1 Melanocortin-1 Receptor-Specific Linear Peptides PALATIN TECHNOLOGIES INC (US) 2017-05-25 — — US disclosed
US-9580466-B2 Melanocortin-1 receptor-specific linear peptides PALATIN TECHNOLOGIES, INC. (US) 2017-02-28 — — US disclosed
US-20150119341-A1 Melanocortin-1 Receptor-Specific Linear Peptides PALATIN TECHNOLOGIES INC (US) 2015-04-30 — — US disclosed
US-8933194-B2 Melanocortin-1 receptor-specific linear peptides PALATIN TECHNOLOGIES, INC. (US) 2015-01-13 — — US disclosed
US-20120225831-A1 Melanocortin-1 Receptor-Specific Linear Peptides PALATIN TECHNOLOGIES, INC. (US) 2012-09-06 — — US disclosed
WO-2011063367-A1 MELANOCORTIN-1 RECEPTOR-SPECIFIC LINEAR PEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2011-05-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170145056-A1 Melanocortin-1 Receptor-Specific Linear Peptides MC1R, MC5R, MC3R CCKBR 71/4885NPY1R 5/4885NPY2R 7/4885
US-20150119341-A1 Melanocortin-1 Receptor-Specific Linear Peptides MC1R, MC3R, MC5R CCKBR 81/4885NPY1R 7/4885NPY2R 12/4885
US-20120225831-A1 Melanocortin-1 Receptor-Specific Linear Peptides MC1R, MC3R, MC5R CCKBR 81/4885NPY1R 7/4885NPY2R 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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