SCHEMBL18556702

SCHEMBL18556702

CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 10/20 0.61
▸ CCKAR P32238 4/20 0.60
▸ OPRD1 P41143 1/20 0.60
▸ KISS1R Q969F8 2/20 0.58
▸ GRPR P30550 2/20 0.55
▸ NPBWR1 P48145 1/20 0.53
▸ MC4R P32245 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18556749 0.99 CCKBR (0.61) CCKBRCCKAROPRD1KISS1RGRPR
SCHEMBL12094758 0.94 MC4R (0.59) CCKBRCCKAROPRD1KISS1RNPBWR1
SCHEMBL16677035 0.94 MC4R (0.59) CCKBRCCKAROPRD1KISS1RNPBWR1
SCHEMBL18556707 0.94 MC4R (0.59) CCKBRCCKAROPRD1KISS1RNPBWR1
SCHEMBL18891478 0.94 MC4R (0.59) CCKBRCCKAROPRD1KISS1RNPBWR1
SCHEMBL18891547 0.94 MC4R (0.59) CCKBRCCKAROPRD1KISS1RNPBWR1
SCHEMBL12094756 0.94 CCKBR (0.56) CCKBRCCKAROPRD1KISS1R
SCHEMBL18891548 0.92 MC4R (0.62) CCKBRKISS1RMC4R
SCHEMBL18891483 0.92 MC4R (0.62) CCKBRKISS1RMC4R
SCHEMBL18556747 0.91 CCKBR (0.58) CCKBRCCKAROPRD1NPBWR1MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170145056-A1 Melanocortin-1 Receptor-Specific Linear Peptides PALATIN TECHNOLOGIES INC (US) 2017-05-25 — — US disclosed
US-9580466-B2 Melanocortin-1 receptor-specific linear peptides PALATIN TECHNOLOGIES, INC. (US) 2017-02-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170145056-A1 Melanocortin-1 Receptor-Specific Linear Peptides MC1R, MC5R, MC3R CCKBR 71/4885CCKAR 26/4885OPRD1 406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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