Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.56 |
| ▸ | CNR1 | P21554 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095761 | 0.81 | CNR2 (0.61) | CNR2CNR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1463796 | 0.81 | CNR2 (0.52) | CNR2CNR1HSD11B1 | |
| SCHEMBL12095569 | 0.78 | CNR2 (0.59) | CNR2CNR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1465040 | 0.77 | HSD11B1 (0.55) | CNR2CNR1HSD11B1 | |
| SCHEMBL3963986 | 0.75 | CNR2 (0.43) | CNR2CNR1ALDH1A1MAPTHSD11B1 | |
| SCHEMBL469406 | 0.75 | CNR2 (1.00) | CNR2CNR1CYP2C8CYP2C9CYP2C19 | |
| SCHEMBL3966458 | 0.74 | CNR2 (0.49) | CNR2CNR1HSD11B1 | |
| SCHEMBL3967901 | 0.73 | FFAR2 (0.49) | CNR2CNR1HSD11B1 | |
| SCHEMBL3962734 | 0.73 | CNR2 (0.91) | CNR2CNR1SMN1; SMN2MAPTHTT | |
| SCHEMBL1463526 | 0.73 | CNR2 (0.75) | CNR2CNR1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-B1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | claimed |