Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.43 |
| ▸ | ELOVL6 | Q9H5J4 | 4/20 | 0.43 |
| ▸ | CCR6 | P51684 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | CCR7 | P32248 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095646 | 0.91 | CCR6 (0.44) | CNR2MAPK14ELOVL6CCR6MAPK13 | |
| SCHEMBL12095619 | 0.87 | CNR2 (0.62) | CNR2MAPK14MAPTLMNAMAPK13 | |
| SCHEMBL12095707 | 0.78 | CNR2 (0.62) | CNR2CCR6MAPTLMNA | |
| SCHEMBL12095788 | 0.78 | GCK (0.49) | CCR6MAPTLMNA | |
| SCHEMBL1464586 | 0.77 | MAPT (0.48) | CNR2MAPK14MAPTMAPK13MAPK12 | |
| SCHEMBL1699062 | 0.76 | MAPK14 (0.61) | CNR2MAPK14MAPTLMNAMAPK13 | |
| SCHEMBL1464751 | 0.76 | MMP2 (0.57) | CNR2MAPT | |
| SCHEMBL12095654 | 0.75 | ALDH1A1 (0.45) | ELOVL6CCR6LMNACCR7 | |
| SCHEMBL1464830 | 0.74 | CNR2 (0.47) | CNR2MAPK14MAPTLMNAMAPK13 | |
| SCHEMBL12095613 | 0.74 | CCR6 (0.66) | CCR6CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-B1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | claimed |