Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 8/20 | 0.54 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1806239 | 0.85 | PRKAA2 (0.47) | PRKAA2MAPK7EPHX2SCN9AMGLL | |
| SCHEMBL1809872 | 0.82 | PRKAA2 (0.49) | PRKAA2MAPK7EPHX2SCN9AMGLL | |
| SCHEMBL1811385 | 0.80 | RBP4 (0.53) | PRKAA2SCN9A | |
| SCHEMBL1810730 | 0.78 | HSD11B1 (0.47) | PRKAA2EPHX2SCN9AMGLLABHD6 | |
| SCHEMBL1806474 | 0.78 | HSD11B1 (0.47) | PRKAA2MAPK7EPHX2SCN9AMGLL | |
| SCHEMBL1806631 | 0.78 | PRKAA2 (0.45) | PRKAA2EPHX2SCN9AMGLLABHD6 | |
| SCHEMBL1809578 | 0.78 | MEN1 (0.47) | PRKAA2EPHX2SCN9AMGLLABHD6 | |
| SCHEMBL1806858 | 0.78 | HSD11B1 (0.52) | PRKAA2MAPK7EPHX2SCN9AMGLL | |
| SCHEMBL1809113 | 0.78 | SCN9A (0.47) | PRKAA2MAPK7EPHX2SCN9AMGLL | |
| SCHEMBL1813141 | 0.77 | PRKAA2 (0.46) | PRKAA2EPHX2SCN9AMGLLHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051296-B2 | Aryl carboxamide derivatives as TTX-S blockers | RAQUALIA PHARMA INC. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | SCN1B, SCN1A, SCN2B | PRKAA2 3288/4885MAPK7 2820/4885EPHX2 2869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.