Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.51 |
| ▸ | DRD2 | P14416 | 8/20 | 0.51 |
| ▸ | DRD3 | P35462 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242501 | 0.85 | ADRB2 (0.75) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL10242515 | 0.81 | ADRB2 (0.68) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL10242428 | 0.76 | ADRB2 (0.62) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL10242335 | 0.75 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL10242408 | 0.75 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL12095843 | 0.75 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL1276374 | 0.75 | ADRB2 (0.81) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL1276054 | 0.75 | ADRB2 (0.81) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL20025035 | 0.73 | ADRB2 (0.69) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL1289938 | 0.72 | ADRB2 (0.71) | ADRB2CHRM3ADRB1ADRA1DDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-B1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2012-09-12 | — | — | EP | disclosed |