Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.59 |
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13327297 | 0.89 | CASP2 (0.67) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL11310865 | 0.88 | FAAH (0.71) | FAAHCASP2DNM1NAAAMEN1 | |
| SCHEMBL1289359 | 0.88 | FAAH (0.71) | FAAHCASP2DNM1NAAAMEN1 | |
| SCHEMBL28488772 | 0.87 | FAAH (0.62) | FAAHCASP2DNM1NAAAMEN1 | |
| SCHEMBL22923620 | 0.86 | FAAH (0.59) | FAAHCASP2DNM1NAAAMEN1 | |
| SCHEMBL22271592 | 0.85 | FAAH (0.78) | FAAHCASP2DNM1NAAAMEN1 | |
| SCHEMBL7693160 | 0.85 | FAAH (0.78) | FAAHCASP2DNM1NAAAMEN1 | |
| SCHEMBL20922221 | 0.85 | FAAH (0.78) | FAAHCASP2DNM1NAAAMEN1 | |
| SCHEMBL9016680 | 0.85 | FAAH (0.78) | FAAHCASP2DNM1NAAAMEN1 | |
| SCHEMBL6682413 | 0.85 | FAAH (0.78) | FAAHCASP2DNM1NAAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514406-A1 | Spontaneously dispersible preconcentrates including a peptide drug in a solid or semisolid carrier | Novo Nordisk A/S (DK) | 2012-10-24 | — | — | EP | disclosed |
| EP-2497462-A1 | Stable non-aqueous pharmaceutical compositions | Novo Nordisk A/S (DK) | 2012-09-12 | — | — | EP | disclosed |