Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.60 |
| ▸ | FOS | P01100 | 1/20 | 0.59 |
| ▸ | JUN | P05412 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | FDPS | P14324 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421074 | 1.00 | MAOB (0.60) | MAOBHCRTR1FOSJUNBCHE | |
| SCHEMBL1210329 | 1.00 | MAOB (0.60) | MAOBHCRTR1FOSJUNBCHE | |
| SCHEMBL1206934 | 0.90 | MAOB (0.52) | MAOBHCRTR1FOSJUNBCHE | |
| SCHEMBL1206933 | 0.90 | MAOB (0.52) | MAOBHCRTR1FOSJUNBCHE | |
| SCHEMBL19244191 | 0.89 | APP (0.60) | MAOBFOSJUNBCHEKDM4E | |
| SCHEMBL19244190 | 0.89 | APP (0.60) | MAOBFOSJUNBCHEKDM4E | |
| SCHEMBL9599969 | 0.88 | KDM4E (0.74) | MAOBHCRTR1KDM4EALDH1A1TTR | |
| SCHEMBL9599975 | 0.88 | KDM4E (0.74) | MAOBHCRTR1KDM4EALDH1A1TTR | |
| SCHEMBL30723822 | 0.88 | FOS (0.56) | MAOBHCRTR1FOSJUNBCHE | |
| SCHEMBL4427604 | 0.88 | TTR (0.69) | MAOBKDM4EALDH1A1TTRDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435572-A | FROM 3-METHOXYBENZALDEHYDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1984-03-06 | — | — | US | claimed |
| CN-108484481-B | Synthesis method of dihydro-1H-indene spiro compound | 遵义医学院 | 2020-06-12 | — | — | CN | disclosed |
| CN-110494413-A | Reduce the compound and application thereof of stench perception | CHEMCOM SA | 2019-11-22 | — | — | CN | disclosed |
| EP-3208301-B1 | RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME | TOSOH CORP (JP) | 2019-04-03 | — | — | EP | disclosed |
| US-10126478-B2 | Resin composition and optical compensation film using same | TOSOH CORPORATION (JP) | 2018-11-13 | — | — | US | disclosed |
| CN-108484481-A | A kind of synthetic method of the spiro-compound of dihydro -1H- indenes | 遵义医学院 | 2018-09-04 | — | — | CN | disclosed |
| US-20170242174-A1 | RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME | TOSOH CORPORATION (JP) | 2017-08-24 | — | — | US | disclosed |
| EP-3208301-A1 | RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME | Tosoh Corporation (JP) | 2017-08-23 | — | — | EP | disclosed |
| EP-2207540-B1 | CYCLOPROPYL ARYL AMIDE DERIVATIVES AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2014-02-26 | — | — | EP | disclosed |
| US-20110044938-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | NYCOMED GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995017393-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-29 | — | — | WO | disclosed |
| US-4845016-A | SHORT DEVELOPMENT TIME, FREE OF BENZYL ALCOHOL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4456682-A | PHOTOSENSITIVITY, PYRAZOLIDONE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-06-26 | — | — | US | disclosed |
| US-4435572-A | FROM 3-METHOXYBENZALDEHYDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1984-03-06 | — | — | US | disclosed |
| US-4409324-A | HIGH BOILING SOLVENT, OIL SOLUBLE PYRAZOLIDONE COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| US-4383027-A | 1-PHENYL-3-ANILINO-4-PHENYLTHIO-5-PYRAZOLONE, 1-PHENYL-3-PYRAZOLIDONE | FUJI PHOTO FILM CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| US-4346224-A | MORPHINE ANALOGS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1982-08-24 | — | — | US | disclosed |
| US-4289882-A | MORPHINE ANALOG ANALGESICS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 1981-09-15 | — | — | US | disclosed |
| US-4189583-A | FROM 1-METHYL-2-OXO-3-METHYLENE-4-(3'-METHOXYPHENYL)-4 -(CARBOXYMETHYLENE)PIPERIDINE BY CYCLIZATION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1980-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110044938-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | BAX, BCL2, BAD | MAOB 2603/4885HCRTR1 2920/4885FOS 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.