Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 1/20 | 0.56 |
| ▸ | JUN | P05412 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1210329 | 0.88 | MAOB (0.60) | FOSJUNMAOBBCHEKDM4E | |
| SCHEMBL1210331 | 0.88 | MAOB (0.60) | FOSJUNMAOBBCHEKDM4E | |
| SCHEMBL29421074 | 0.88 | MAOB (0.60) | FOSJUNMAOBBCHEKDM4E | |
| SCHEMBL10771831 | 0.84 | L3MBTL1 (0.56) | MAOBKDM4ESMN1; SMN2MAOAMAPT | |
| SCHEMBL10771830 | 0.84 | L3MBTL1 (0.56) | MAOBKDM4ESMN1; SMN2MAOAMAPT | |
| SCHEMBL10394709 | 0.82 | KMT2A (0.59) | MAOBKDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL10394710 | 0.82 | KMT2A (0.59) | MAOBKDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL15164723 | 0.82 | KMT2A (0.59) | MAOBKDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL1206933 | 0.82 | MAOB (0.52) | FOSJUNMAOBBCHEKDM4E | |
| SCHEMBL1206934 | 0.82 | MAOB (0.52) | FOSJUNMAOBBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |