Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979619 | 0.90 | SMN1; SMN2 (0.42) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10096177 | 0.85 | ALDH1A1 (0.41) | LMNACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL10096180 | 0.84 | GRIK2 (0.39) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10096256 | 0.82 | SMN1; SMN2 (0.43) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10096176 | 0.81 | GRIK2 (0.40) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12408281 | 0.80 | SMN1; SMN2 (0.41) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10193404 | 0.80 | CYP1A2 (0.41) | LMNACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL10096178 | 0.78 | GRIK2 (0.37) | LMNACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL10095631 | 0.78 | SMN1; SMN2 (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL13151738 | 0.78 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110268698-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110268698-A1 | METHODS FOR TREATING HEPATITIS C | HAVCR2, LIPC, HCCS | LMNA 1241/4885CYP1A2 623/4885CYP2C9 1068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.