Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12109291 | 1.00 | PDK2 (0.50) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL12776583 | 0.95 | PDK2 (0.46) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL12723263 | 0.92 | PDK2 (0.57) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL25012048 | 0.86 | PDK2 (0.55) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL29371027 | 0.83 | PDK2 (0.67) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL21585297 | 0.83 | PDK2 (0.39) | PDK2PDK4HTR5AMAPTKMT2A | |
| SCHEMBL31911 | 0.83 | PDK2 (0.67) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL15046241 | 0.83 | PDK2 (0.36) | PDK2PDK4ALDH1A1PGR | |
| SCHEMBL28706253 | 0.81 | PDK2 (0.64) | PDK2PDK4HTR5AGAAMAPT | |
| SCHEMBL12776293 | 0.81 | PDK2 (0.50) | PDK2PDK4HTR5AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034485-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-9034485-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-20110266533-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| US-20110266533-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| WO-2010083871-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110266533-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | SLCO2A1, SLC40A1, TOE1 | PDK2 1970/4885PDK4 2479/4885HTR5A 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.