SCHEMBL12776293

SCHEMBL12776293

CC1(C)c2ccccc2Nc2cc3ccccc3cc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 1/20 0.50
▸ PDK4 Q16654 1/20 0.50
▸ GAA P10253 3/20 0.43
▸ MAPT P10636 3/20 0.43
▸ NOX1 Q9Y5S8 3/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ HTR5A P47898 2/20 0.38
▸ RAD52 P43351 1/20 0.34
▸ PGR P06401 3/20 0.33
▸ LMNA P02545 2/20 0.32
▸ HTR2A P28223 1/20 0.32
▸ KMT2A Q03164 2/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30271921 1.00 PDK2 (0.50) PDK2PDK4GAAMAPTNOX1
SCHEMBL12776857 0.92 GAA (0.44) PDK2PDK4GAAMAPTNOX1
SCHEMBL12723263 0.88 PDK2 (0.57) PDK2PDK4GAAMAPTNOX1
SCHEMBL25012048 0.86 PDK2 (0.55) PDK2PDK4GAAMAPTNOX1
SCHEMBL16372499 0.84 CYP1A2 (0.47) PDK2PDK4GAAMAPTNOX1
SCHEMBL31911 0.83 PDK2 (0.67) PDK2PDK4GAAMAPTNOX1
SCHEMBL29371027 0.83 PDK2 (0.67) PDK2PDK4GAAMAPTNOX1
SCHEMBL28706253 0.81 PDK2 (0.64) PDK2PDK4GAAMAPTNOX1
SCHEMBL12109291 0.81 PDK2 (0.50) PDK2PDK4GAAMAPTHTR5A
SCHEMBL12109367 0.81 PDK2 (0.50) PDK2PDK4GAAMAPTHTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4265624-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME Lg Chem, Ltd. (KR) 2023-10-25 — — EP disclosed
EP-4265624-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME Lg Chem, Ltd. (KR) 2023-10-25 — — EP disclosed
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND LG CHEM, LTD. (KR) 2023-10-05 — — US disclosed
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND LG CHEM, LTD. (KR) 2023-10-05 — — US disclosed
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND LG CHEM, LTD. (KR) 2023-10-05 — — US disclosed
EP-4194460-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND Lg Chem, Ltd. (KR) 2023-06-14 — — EP disclosed
CN-115989725-A Compound and organic light emitting device including the same 株式会社LG化学 2023-04-18 — — CN disclosed
CN-115968592-A Organic light emitting device comprising organic compound 株式会社LG化学 2023-04-14 — — CN disclosed
WO-2022139513-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2022-06-30 — — WO disclosed
WO-2022139525-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND 주식회사 엘지화학 2022-06-30 — — WO disclosed
WO-2022139525-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND 주식회사 엘지화학 2022-06-30 — — WO disclosed
US-11349085-B2 Acridine derivatives and organic electroluminescent device WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-05-31 — — US disclosed
US-20200161561-A1 ACRIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-05-21 — — US disclosed
EP-2306541-A1 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods Fujifilm Corporation (JP) 2011-04-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200161561-A1 ACRIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE ACR, KCNH1, TRPA1 PDK2 987/4885PDK4 1243/4885GAA 330/4885
US-11349085-B2 Acridine derivatives and organic electroluminescent device ACR, KCNH1, TRPA1 PDK2 987/4885PDK4 1243/4885GAA 330/4885
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND CYP1A1, AOX1, CYP1B1 PDK2 3421/4885PDK4 3187/4885GAA 2399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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