Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | DRD1 | P21728 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12110142 | 0.80 | MAOA (0.35) | MAOADRD1HIF1AHSD17B10MAPK1 | |
| SCHEMBL1295143 | 0.80 | ESR1 (0.41) | MAOADRD1HIF1AHSD17B10MAPK1 | |
| SCHEMBL1294025 | 0.78 | ESR2 (0.46) | MAOAMAPK1KDM4EMAPT | |
| SCHEMBL11341983 | 0.77 | AHR (0.38) | MAOAHIF1AHSD17B10MAPK1DRD2 | |
| SCHEMBL12110115 | 0.76 | PPARA (0.37) | HSD17B10MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL3783758 | 0.69 | HSP90AA1 (0.45) | DRD1HSD17B10THPODRD2TSHR | |
| SCHEMBL12110414 | 0.67 | GAA (0.35) | HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL4041645 | 0.65 | HTT (0.47) | HSD17B10MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL31009038 | 0.65 | HTT (0.47) | HSD17B10MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL3895440 | 0.65 | HTT (0.47) | HSD17B10MAPK1KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269744-A1 | Benzazepine Compound | ASTELLAS PHARMA INC. (JP) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269744-A1 | Benzazepine Compound | HTR2C, HTR3C, HTR2A | MAOA 124/4885DRD1 254/4885HIF1A 4267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.