Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | OGG1 | O15527 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12115952 | 0.90 | CNR2 (0.48) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL23785455 | 0.88 | TSHR (0.46) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL31404067 | 0.88 | KDM4E (0.62) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL1308527 | 0.86 | HPGD (0.49) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL1308523 | 0.86 | HPGD (0.49) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL1307343 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL1307346 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL1306696 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDTDP1TSHR | |
| SCHEMBL1306700 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDTDP1TSHR | |
| SCHEMBL1308006 | 0.83 | KMT2A (0.48) | ALDH1A1KDM4EHPGDTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |