Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | OGG1 | O15527 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12113399 | 0.89 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL12116456 | 0.88 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL3816749 | 0.83 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL3816745 | 0.83 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDTDP1OGG1 | |
| SCHEMBL1308523 | 0.82 | HPGD (0.49) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL1308527 | 0.82 | HPGD (0.49) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL1308003 | 0.81 | KMT2A (0.48) | KDM4EALDH1A1HPGDTDP1LMNA | |
| SCHEMBL1308006 | 0.81 | KMT2A (0.48) | KDM4EALDH1A1HPGDTDP1LMNA | |
| SCHEMBL1307346 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL1307343 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDTDP1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12194002-B2 | Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dibromodulcitol | BROWN DENNIS (US) | 2025-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12194002-B2 | Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dibromodulcitol | HEXD, DDOST, PAICS | KDM4E 1849/4885ALDH1A1 658/4885HPGD 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.