Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14296706 | 0.90 | EGFR (0.32) | FLT3EGFRERBB2 | |
| SCHEMBL12117242 | 0.88 | PGR (0.34) | PGR | |
| SCHEMBL12117247 | 0.87 | PGR (0.41) | PGR | |
| SCHEMBL2609857 | 0.85 | KDM4E (0.40) | FLT3NTSR1 | |
| SCHEMBL12117270 | 0.83 | PDK2 (0.35) | PGR | |
| SCHEMBL26813251 | 0.83 | NTSR1 (0.34) | PGRNTSR1 | |
| SCHEMBL12116343 | 0.81 | KDM4E (0.37) | NTSR1 | |
| SCHEMBL12117248 | 0.81 | PGR (0.35) | PGR | |
| SCHEMBL802510 | 0.81 | KDM4E (0.40) | FLT3NTSR1 | |
| SCHEMBL12117253 | 0.81 | PGR (0.40) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-9475792-B2 | Materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2016-10-25 | — | — | US | disclosed |
| US-9475792-B2 | Materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2016-10-25 | — | — | US | disclosed |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20110272684-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-11-10 | — | — | US | disclosed |
| US-20110272684-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-11-10 | — | — | US | disclosed |
| WO-2011107186-A2 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-09-09 | — | — | WO | disclosed |
| WO-2010083872-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP1B1, CYP1A1, CYP2E1 | FLT3 1205/4885EGFR 1825/4885ERBB2 1570/4885 |
| US-20110272684-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | SLCO4C1, SLCO2A1, SLCO1A2 | FLT3 3259/4885EGFR 1835/4885ERBB2 3504/4885 |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP1B1, CYP1A1, CYP2E1 | FLT3 1205/4885EGFR 1825/4885ERBB2 1570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.