SCHEMBL12117307

SCHEMBL12117307

Cc1cc(C#N)cc(C(=O)NC(C)C)c1NC(=O)c1cc(Cn2cc(C(F)(F)C(F)(F)F)nn2)nn1-c1ncccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 11/20 0.35
SLC2A3 P11169 11/20 0.35
SLC2A4 P14672 11/20 0.35
SLC2A2 P11168 5/20 0.35
KCNH2 Q12809 4/20 0.32
GCK P35557 3/20 0.32
DHODH Q02127 2/20 0.32
CACNA1G O43497 2/20 0.31
CACNA1H O95180 2/20 0.31
CYP3A4 P08684 2/20 0.31
CACNA1C Q13936 2/20 0.31
CACNA1I Q9P0X4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12116570 0.97 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2KCNH2
SCHEMBL12113464 0.95 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2KCNH2
SCHEMBL12113378 0.95 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2KCNH2
SCHEMBL12117282 0.93 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL12117077 0.92 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL12117039 0.92 DHODH (0.33) DHODH
SCHEMBL15255551 0.91 DHODH (0.33) DHODH
SCHEMBL12117349 0.91 RORC (0.36) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL12117005 0.90 SLC2A1 (0.32) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL12117091 0.90 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8536202-B2 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US disclosed
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides AADAC, NAAA, ANTXR2 SLC2A1 4803/4885SLC2A3 4685/4885SLC2A4 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.