SCHEMBL12118656

SCHEMBL12118656

CC(=O)[C@@H](C)CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.68
▸ FOLH1 Q04609 3/20 0.43
▸ NOD1 Q9Y239 2/20 0.41
▸ CCKAR P32238 5/20 0.41
▸ CCKBR P32239 5/20 0.41
▸ GLO1 Q04760 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16638275 1.00 GLP1R (0.68) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL12118666 1.00 GLP1R (0.68) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL16711028 1.00 GLP1R (0.68) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL16638310 1.00 GLP1R (0.68) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL16947835 1.00 GLP1R (0.68) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL12118710 1.00 GLP1R (0.68) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL17127177 0.99 GLP1R (0.67) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL15355763 0.99 GLP1R (0.67) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL17127178 0.99 GLP1R (0.67) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL20900397 0.94 GLP1R (0.70) GLP1RFOLH1NOD1CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230126068-A1 Insulin Derivative GAN & LEE PHARMACEUTICALS CO., LTD. (CN) 2023-04-27 — — US disclosed
US-20150274801-A1 ACYLATED GLUCAGON ANALOGUES NOVO NORDISK AS (DK) 2015-10-01 — — US disclosed
US-9006178-B2 Double-acylated GLP-1 derivatives with a linker NOVO NORDISK A/S (DK) 2015-04-14 — — US disclosed
US-20110275559-A1 Long-Acting Y2 and/or Y4 Receptor Agonists NOVO NORDISK A/S (DK) 2011-11-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230126068-A1 Insulin Derivative IAPP, GLP1R, INSR GLP1R 2/4885FOLH1 3068/4885NOD1 909/4885
US-20150274801-A1 ACYLATED GLUCAGON ANALOGUES GLP1R, GCG, IAPP GLP1R 1/4885FOLH1 352/4885NOD1 2294/4885
US-20110275559-A1 Long-Acting Y2 and/or Y4 Receptor Agonists NPY4R, NPY1R, NPY2R GLP1R 6/4885FOLH1 2539/4885NOD1 2426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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