SCHEMBL20900397

SCHEMBL20900397

C[C@@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.70
▸ FOLH1 Q04609 4/20 0.44
▸ NOD1 Q9Y239 2/20 0.43
▸ CCKAR P32238 4/20 0.42
▸ CCKBR P32239 4/20 0.42
▸ GLO1 Q04760 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12071818 1.00 GLP1R (0.70) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL13147099 0.95 GLP1R (0.65) GLP1RFOLH1NOD1GLO1
SCHEMBL13147072 0.95 GLP1R (0.65) GLP1RFOLH1NOD1GLO1
SCHEMBL13147035 0.95 GLP1R (0.65) GLP1RFOLH1NOD1GLO1
SCHEMBL13147005 0.95 GLP1R (0.65) GLP1RFOLH1NOD1GLO1
SCHEMBL19227334 0.94 GLP1R (0.77) GLP1RCCKARCCKBR
SCHEMBL12118710 0.94 GLP1R (0.68) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL12118656 0.94 GLP1R (0.68) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL16638275 0.94 GLP1R (0.68) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL16711028 0.94 GLP1R (0.68) GLP1RFOLH1NOD1CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10259856-B2 Protease stabilized acylated insulin analogues NOVO NORDISK A/S (DK) 2019-04-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10259856-B2 Protease stabilized acylated insulin analogues IAPP, IDE, LIPE GLP1R 54/4885FOLH1 524/4885NOD1 3835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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