SCHEMBL12118741

SCHEMBL12118741

CC(=O)[C@@H](C)CCCCNC(=O)COCCOCCNC(=O)COCCOCCN

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.41
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ FAAH O00519 1/20 0.35
▸ ADRB2 P07550 1/20 0.34
▸ HTR1A P08908 1/20 0.34
▸ PAOX Q6QHF9 2/20 0.33
▸ SIRT6 Q8N6T7 1/20 0.32
▸ SIRT1 Q96EB6 1/20 0.32
▸ GNAI3 P08754 1/20 0.32
▸ GNAO1 P09471 1/20 0.32
▸ GNAI1 P63096 1/20 0.32
▸ TLR2 O60603 2/20 0.32
▸ TSHR P16473 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ DPP7 Q9UHL4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12118613 0.90 GLP1R (0.42) GLP1RMEN1KMT2AFAAHPAOX
SCHEMBL14683527 0.88 GLP1R (0.44) GLP1RMEN1KMT2AFAAHTSHR
SCHEMBL14683467 0.88 GLP1R (0.44) GLP1RMEN1KMT2AFAAHTSHR
SCHEMBL71906 0.88 MEN1 (0.45) GLP1RMEN1KMT2AFAAHTSHR
SCHEMBL71147 0.88 GLP1R (0.46) GLP1RMEN1KMT2AFAAHTSHR
SCHEMBL14683460 0.88 GLP1R (0.41) GLP1RMEN1KMT2AFAAHTSHR
SCHEMBL71315 0.88 GLP1R (0.46) GLP1RMEN1KMT2AFAAHTSHR
SCHEMBL13805652 0.86 GLP1R (0.49) GLP1RMEN1KMT2AFAAHTSHR
SCHEMBL14683575 0.85 FAAH (0.43) GLP1RMEN1KMT2AFAAHTSHR
SCHEMBL13805654 0.85 GLP1R (0.53) GLP1RMEN1KMT2AFAAHTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11633459-B2 GIP derivatives and uses thereof NOVO NORDISK A/S (DK) 2023-04-25 — — US disclosed
US-20220000982-A1 GIP DERIVATIVES AND USES THEREOF NOVO NORDISK A/S (DK) 2022-01-06 — — US disclosed
US-20110275559-A1 Long-Acting Y2 and/or Y4 Receptor Agonists NOVO NORDISK A/S (DK) 2011-11-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220000982-A1 GIP DERIVATIVES AND USES THEREOF GIPR, GLP1R, GPR119 GLP1R 2/4885MEN1 1878/4885KMT2A 4381/4885
US-11633459-B2 GIP derivatives and uses thereof GIPR, GLP1R, GPR119 GLP1R 2/4885MEN1 1878/4885KMT2A 4381/4885
US-20110275559-A1 Long-Acting Y2 and/or Y4 Receptor Agonists NPY4R, NPY1R, NPY2R GLP1R 6/4885MEN1 2452/4885KMT2A 4226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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