⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035 | 0.91 | — | — | |
| SCHEMBL12124 | 0.88 | — | — | |
| SCHEMBL11480 | 0.79 | — | — | |
| SCHEMBL6087 | 0.73 | — | — | |
| SCHEMBL5704 | 0.72 | SLC6A2 (0.55) | — | |
| SCHEMBL5801 | 0.71 | SLC6A2 (0.53) | — | |
| SCHEMBL4964015 | 0.71 | ALDH1A1 (0.50) | — | |
| SCHEMBL10867 | 0.70 | SLC6A2 (0.58) | — | |
| SCHEMBL5656 | 0.70 | SLC6A2 (0.58) | — | |
| SCHEMBL10999 | 0.70 | SLC6A2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |