Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13766488 | 0.85 | ALDH1A1 (0.53) | ALDH1A1ALOX12TSHRGRM2MEN1 | |
| SCHEMBL8276621 | 0.84 | TP53 (0.42) | ALDH1A1ALOX12TSHRGRM2HRH3 | |
| SCHEMBL11941068 | 0.83 | ALDH1A1 (0.54) | ALDH1A1ALOX12TSHRGRM2MEN1 | |
| SCHEMBL27592520 | 0.83 | HRH3 (0.47) | ALDH1A1ALOX12MEN1KMT2AACACB | |
| SCHEMBL20365507 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ALOX12TSHRGRM2ACACB | |
| SCHEMBL2242868 | 0.80 | PARP10 (0.55) | ALDH1A1ALOX12TSHRGRM2HRH3 | |
| SCHEMBL18715290 | 0.79 | ALDH1A1 (0.50) | ALDH1A1ALOX12TSHRGRM2MEN1 | |
| SCHEMBL8497080 | 0.79 | ALDH1A1 (0.71) | ALDH1A1ALOX12TSHRGRM2MEN1 | |
| SCHEMBL7102647 | 0.79 | KMT2A (0.55) | ALDH1A1TSHRMEN1KMT2AHRH3 | |
| SCHEMBL2298560 | 0.79 | TP53 (0.40) | ALDH1A1MEN1KMT2AACACBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314725-B1 | SULFONIUM SALT COMPOUND | WAKO PURE CHEM IND LTD (JP) | 2008-03-19 | — | — | EP | disclosed |
| US-6924323-B2 | Sulfonium salt compound | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-02 | — | — | US | disclosed |
| US-20040033434-A1 | Sulfonium salt compound | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2004-02-19 | — | — | US | disclosed |
| EP-1314725-A1 | SULFONIUM SALT COMPOUND | Wako Pure Chemical Industries, Ltd. (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0070134-B1 | SECONDARY PHENYL ETHANOL AMINES AND THEIR PHARMACEUTICAL USE | BEECHAM GROUP PLC (GB) | 1985-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040033434-A1 | Sulfonium salt compound | SPIN1, RER1, SPIN2B | ALDH1A1 2370/4885ALOX12 4066/4885TSHR 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.