SCHEMBL121275

SCHEMBL121275

COC(=O)N(C)N(C)C(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.73

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.40
▸ MALT1 Q9UDY8 14/20 0.34
▸ RBP4 P02753 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29416641 1.00 DHODH (0.40) DHODHMALT1RBP4
SCHEMBL13072495 0.94 DHODH (0.40) DHODHMALT1RBP4
SCHEMBL13318673 0.94 DHODH (0.40) DHODHMALT1RBP4
SCHEMBL12528067 0.92 DHODH (0.39) DHODHMALT1RBP4
SCHEMBL30978015 0.92 DHODH (0.41) DHODHMALT1
SCHEMBL12527884 0.92 DHODH (0.41) DHODHMALT1
SCHEMBL2594967 0.92 DHODH (0.41) DHODHMALT1
SCHEMBL17962419 0.91 DHODH (0.40) DHODHMALT1RBP4
SCHEMBL12559377 0.91 DHODH (0.39) DHODHMALT1
SCHEMBL31513875 0.90 DHODH (0.40) DHODHMALT1RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3646731-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-05-06 — — EP claimed
EP-3300602-B1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-03-25 — — EP claimed
EP-3300602-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2018-04-04 — — EP claimed
US-20160219872-A1 Foamable Pesticide Compositions And Methods Of Application BASF CORPORATION 2016-08-04 — — US claimed
US-9339030-B2 Foamable pesticide compositions and methods of application BASF CORPORATION (US) 2016-05-17 — — US claimed
US-20150105258-A1 Methods For Controlling Pests BASF CORPORATION (US) 2015-04-16 — — US claimed
US-8940662-B2 Methods for controlling pests BASF CORPORATION (US) 2015-01-27 — — US claimed
WO-2014063942-A1 SUBSTITUTED PESTICIDAL PYRAZOLE COMPOUNDS BASF SE (DE) 2014-05-01 — — WO claimed
US-20140013654-A1 Foamable Pesticide Compositions BASF CORPORATION 2014-01-16 — — US claimed
US-20140017216-A1 PESTICIDAL MIXTURES BAYER CROPSCIENCE LP (US) 2014-01-16 — — US claimed
EP-2424370-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF Corporation (US) 2012-03-07 — — EP claimed
EP-2424347-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF Corporation (US) 2012-03-07 — — EP claimed
WO-2011147952-A1 PESTICIDAL MIXTURES BASF SE (DE) 2011-12-01 — — WO claimed
US-20110118212-A1 Pestcidal active mixtures comprising isoxazoline compounds I BASF SE (DE) 2011-05-19 — — US claimed
WO-2011025789-A2 FOAMABLE PESTICIDE COMPOSITIONS AND METHODS OF APPLICATION BASF CORPORATION (US) 2011-03-03 — — WO claimed
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-12-23 — — US claimed
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-12-23 — — US claimed
US-20100322990-A1 METHODS FOR CONTROLLING PESTS BASF CORPORATION (US) 2010-12-23 — — US claimed
WO-2010129345-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-11-11 — — WO claimed
WO-2010127019-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-11-04 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS DDT, PON1, ACHE DHODH 718/4885MALT1 4476/4885RBP4 447/4885
US-20110118212-A1 Pestcidal active mixtures comprising isoxazoline compounds I CHRM3, CHRM5, CHRM1 DHODH 4306/4885MALT1 4326/4885RBP4 3465/4885
US-20100322990-A1 METHODS FOR CONTROLLING PESTS DDT, ACHE, PON1 DHODH 1877/4885MALT1 4338/4885RBP4 482/4885
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS DDT, ACHE, CHRM2 DHODH 2887/4885MALT1 2349/4885RBP4 944/4885
US-20140013654-A1 Foamable Pesticide Compositions DDT, PON1, ACHE DHODH 718/4885MALT1 4476/4885RBP4 447/4885
US-20150105258-A1 Methods For Controlling Pests DDT, ACHE, PON1 DHODH 1877/4885MALT1 4338/4885RBP4 482/4885
US-20160219872-A1 Foamable Pesticide Compositions And Methods Of Application DDT, PLD1, ACHE DHODH 1116/4885MALT1 3749/4885RBP4 1905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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