SCHEMBL13318673

SCHEMBL13318673

COC(=O)N(C)N(C)C(=O)c1cc(Cl)cc(Cl)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.40
▸ RBP4 P02753 1/20 0.33
▸ POLB P06746 1/20 0.32
▸ MALT1 Q9UDY8 7/20 0.31
▸ KMT2A Q03164 3/20 0.31
▸ MEN1 O00255 2/20 0.31
▸ PSD A5PKW4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29416641 0.94 DHODH (0.40) DHODHRBP4MALT1
SCHEMBL121275 0.94 DHODH (0.40) DHODHRBP4MALT1
SCHEMBL12528140 0.92 DHODH (0.39) DHODHRBP4MALT1KMT2APSD
SCHEMBL10028783 0.90 DHODH (0.41) DHODHRBP4MALT1KMT2AMEN1
SCHEMBL123506 0.89 DHODH (0.40) DHODHRBP4MALT1KMT2AMEN1
SCHEMBL29458550 0.89 DHODH (0.40) DHODHRBP4MALT1KMT2AMEN1
SCHEMBL29360347 0.89 DHODH (0.40) DHODHRBP4MALT1KMT2AMEN1
SCHEMBL950260 0.89 DHODH (0.41) DHODHRBP4MALT1KMT2APSD
SCHEMBL13072493 0.88 DHODH (0.43) DHODHRBP4
SCHEMBL13072495 0.88 DHODH (0.40) DHODHRBP4MALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 — — US disclosed
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-22 — — US disclosed
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC1, UQCRC2, Q6ZSR9 DHODH 277/4885RBP4 1463/4885POLB 364/4885
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC2, UQCRC1, UQCRB DHODH 558/4885RBP4 1490/4885POLB 190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback