Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504163 | 0.88 | HDAC3 (0.46) | HDAC3HDAC6HDAC8HDAC11SMN1; SMN2 | |
| SCHEMBL14878028 | 0.84 | KMT2A (0.44) | NQO2SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL13213695 | 0.83 | HDAC3 (0.47) | HDAC3HDAC6HDAC8HDAC11SMN1; SMN2 | |
| SCHEMBL13283420 | 0.79 | HPSE (0.41) | MAPTNR1H4HDAC1HDAC2 | |
| SCHEMBL22920719 | 0.77 | PGR (0.48) | SMN1; SMN2MAPTTP53TRPV1NPC1 | |
| SCHEMBL13924222 | 0.76 | AR (0.41) | HDAC3HDAC6HDAC8HDAC11TP53 | |
| SCHEMBL13866520 | 0.75 | NAMPT (0.37) | HDAC3HDAC6HDAC8TP53RAB9A | |
| SCHEMBL13283327 | 0.74 | PTGS1 (0.50) | NQO2HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL24169215 | 0.73 | HDAC3 (0.48) | HDAC3HDAC6HDAC8HDAC11SMN1; SMN2 | |
| SCHEMBL12355630 | 0.73 | HDAC2 (0.57) | HDAC3HDAC6HDAC8SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304508-B2 | Fluorine-containing dicarboxylic acids and their novel polymer compounds | CENTRAL GLASS COMPANY, LIMITED (JP) | 2012-11-06 | — | — | US | disclosed |
| US-20110282026-A1 | Fluorine-Containing Dicarboxylic Acids and Their Novel Polymer Compounds | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-11-17 | — | — | US | disclosed |