Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13213695 | 0.95 | HDAC3 (0.47) | HDAC3HDAC6HDAC11HDAC8TRPV1 | |
| SCHEMBL12128359 | 0.88 | NQO2 (0.44) | HDAC3HDAC6HDAC11HDAC8TRPV1 | |
| SCHEMBL22920719 | 0.88 | PGR (0.48) | TRPV1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL13866520 | 0.86 | NAMPT (0.37) | HDAC3HDAC6HDAC8RAB9AMEN1 | |
| SCHEMBL13283420 | 0.85 | HPSE (0.41) | NR1H4MAPTHDAC1HDAC2 | |
| SCHEMBL24169215 | 0.84 | HDAC3 (0.48) | HDAC3HDAC6HDAC11HDAC8TRPV1 | |
| SCHEMBL12355630 | 0.81 | HDAC2 (0.57) | HDAC3HDAC6HDAC8TRPV1SMN1; SMN2 | |
| SCHEMBL13537154 | 0.75 | NR1H4 (0.44) | HDAC3HDAC6HDAC11HDAC8TRPV1 | |
| SCHEMBL13283413 | 0.74 | HDAC1 (0.42) | NR1H4MAPTHDAC1HDAC2 | |
| SCHEMBL17735576 | 0.73 | NPC1 (0.53) | HDAC3HDAC6HDAC11HDAC8TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395040-A1 | FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM | Central Glass Company, Limited (JP) | 2011-12-14 | — | — | EP | disclosed |