Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11570592 | 0.88 | — | — | |
| SCHEMBL20234024 | 0.83 | TSHR (0.34) | DAOMAOBKDM1ASIGMAR1PIK3CD | |
| SCHEMBL10289113 | 0.81 | ALDH1A1 (0.35) | KDM2BPIK3CDKDM4EALDH1A1MAPT | |
| SCHEMBL27420657 | 0.80 | SLC18A3 (0.45) | SIGMAR1PIK3CDKDM4EALDH1A1MAPT | |
| SCHEMBL20725092 | 0.80 | KDM4E (0.43) | DAOMAOBKDM1AHRH3KDM4E | |
| SCHEMBL4912757 | 0.80 | DAO (0.33) | DAOMAOBKDM1ASIGMAR1PIK3CD | |
| SCHEMBL14725165 | 0.80 | SLC18A3 (0.45) | SIGMAR1PIK3CDKDM4EALDH1A1MAPT | |
| SCHEMBL27420652 | 0.80 | SLC18A3 (0.45) | SIGMAR1PIK3CDKDM4EALDH1A1MAPT | |
| SCHEMBL24713588 | 0.79 | KDM4E (0.42) | KDM2BSIGMAR1PIK3CDKDM4EALDH1A1 | |
| SCHEMBL22550677 | 0.79 | KDM4E (0.42) | KDM2BSIGMAR1PIK3CDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183936-A2 | COMBINATION THERAPY OF A PI3K INHIBITOR AND KRAS INHIBITOR AND METHODS OF USE THEREOF | TOTUS MEDICINES INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| US-8063229-B2 | Antifungal triazole derivatives, method for the preparation thereof and pharmaceutical composition containing same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2011-11-22 | — | — | US | disclosed |
| US-20100063285-A1 | ANTIFUNGAL TRIAZOLE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063285-A1 | ANTIFUNGAL TRIAZOLE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CYP51A1, ERG28, CYP3A5 | DAO 644/4885MAOB 362/4885KDM1A 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.