Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961259 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAUSP2GAA | |
| SCHEMBL12225637 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNAKMT2ASLC22A2 | |
| SCHEMBL407525 | 0.82 | USP2 (0.48) | ALDH1A1TSHRKMT2AUSP2GAA | |
| SCHEMBL13266443 | 0.82 | TSHR (0.65) | ALDH1A1TSHRLMNAKMT2ASLC22A2 | |
| SCHEMBL14607022 | 0.81 | GAA (0.37) | TSHRCYP2D6USP2GAA | |
| SCHEMBL14153993 | 0.81 | TSHR (0.61) | ALDH1A1TSHRKMT2AUSP2GAA | |
| SCHEMBL12464697 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAKMT2ASLC22A2 | |
| SCHEMBL3664738 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAKMT2ASLC22A2 | |
| SCHEMBL17853878 | 0.77 | USP2 (0.50) | ALDH1A1TSHRKMT2AMAPK1USP2 | |
| SCHEMBL5021623 | 0.77 | TSHR (0.50) | TSHRKMT2AUSP2GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889146-A1 | POLYHETEROCYCLIC TLR7/8 ANTAGONISTS AND THEIR USES FOR TREATING IMMUNE DISORDERS | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |
| US-8063162-B2 | Polymer for an ink receiving layer of an inkjet recording element | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110160416-A1 | POLYMER FOR AN INK RECEIVING LAYER OF AN INKJET RECORDING ELEMENT | CHEN TIENTEH | 2011-06-30 | — | — | US | disclosed |
| US-7923117-B2 | first monomer of the polymer includes at least one amine functional group; aminoethylmethacrylate; aminoethylacrylate; second monomer includes a carbon backbone having at least one silane functional group pendant; prevent dye from migrating | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-04-12 | — | — | US | disclosed |
| US-20080182936-A1 | POLYMER FOR AN INK RECEIVING LAYER OF AN INKJET RECORDING ELEMENT | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2008-07-31 | — | — | US | disclosed |