Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12225637 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNAKMT2ASLC22A2 | |
| SCHEMBL12130522 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAKMT2ASLC22A2 | |
| SCHEMBL3677891 | 0.79 | USP2 (0.50) | ALDH1A1TSHRLMNAKMT2ACYP2C19 | |
| SCHEMBL13266443 | 0.78 | TSHR (0.65) | ALDH1A1TSHRLMNAKMT2ASLC22A2 | |
| SCHEMBL11950437 | 0.77 | — | — | |
| SCHEMBL12310672 | 0.77 | — | — | |
| SCHEMBL12310728 | 0.77 | — | — | |
| SCHEMBL3664738 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAKMT2ASLC22A2 | |
| SCHEMBL4940443 | 0.74 | KMT2A (0.59) | ALDH1A1TSHRLMNAKMT2ASLC22A2 | |
| SCHEMBL13655355 | 0.74 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNAKMT2ASLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10022469-B2 | Microspheres useful for therapeutic vascular embolization | BioSphere Medical, SA (US) | 2018-07-17 | — | — | US | disclosed |
| US-20160361458-A1 | MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR EMBOLIZATION | BIOSPHERE MEDICAL SA (FR) | 2016-12-15 | — | — | US | disclosed |
| US-9439861-B2 | Microspheres useful for therapeutic vascular embolization | BioSphere Medical, SA (US) | 2016-09-13 | — | — | US | disclosed |
| US-20130252900-A1 | MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR EMBOLIZATION | BioSphere Medical, SA (US) | 2013-09-26 | — | — | US | disclosed |
| US-20110182998-A1 | MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR EMBOLIZATION | BIOSPHERE MEDICAL, INC. (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252900-A1 | MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR EMBOLIZATION | CD68, FGB, MB | ALDH1A1 2248/4885TSHR 2807/4885LMNA 406/4885 |
| US-10022469-B2 | Microspheres useful for therapeutic vascular embolization | CD68, FGB, MB | ALDH1A1 2248/4885TSHR 2807/4885LMNA 406/4885 |
| US-20160361458-A1 | MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR EMBOLIZATION | CD68, FGB, MB | ALDH1A1 2248/4885TSHR 2807/4885LMNA 406/4885 |
| US-20110182998-A1 | MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR EMBOLIZATION | CD68, FGB, MB | ALDH1A1 2248/4885TSHR 2807/4885LMNA 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.