SCHEMBL12133671

SCHEMBL12133671

Cc1ccc2c(c1)C1(c3cc(C)ccc3-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc31)c1cc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)ccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 4/20 0.46
▸ MEN1 O00255 7/20 0.44
▸ KMT2A Q03164 7/20 0.44
▸ ALDH1A1 P00352 5/20 0.44
▸ HPGD P15428 4/20 0.44
▸ MAPT P10636 3/20 0.44
▸ RAB9A P51151 4/20 0.43
▸ NPC1 O15118 3/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ TP53 P04637 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ KDM4E B2RXH2 3/20 0.42
▸ NFKB1 P19838 1/20 0.41
▸ NFKB2 Q00653 1/20 0.41
▸ RELA Q04206 1/20 0.41
▸ NTSR1 P30989 1/20 0.40
▸ PDK2 Q15119 2/20 0.40
▸ CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16175924 0.96 PDK2 (0.43) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL25946577 0.94 PDK2 (0.44) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL25464734 0.94 PDK2 (0.44) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL12133792 0.89 L3MBTL1 (0.44) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL12390405 0.89 L3MBTL1 (0.61) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL19164605 0.88 PDK2 (0.47) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL19743182 0.88 L3MBTL1 (0.43) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL19743185 0.88 L3MBTL1 (0.43) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL2605985 0.88 L3MBTL1 (0.46) L3MBTL1MEN1KMT2AALDH1A1HPGD
SCHEMBL21230735 0.87 PDK2 (0.46) L3MBTL1MEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3457450-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-12 — — EP disclosed
EP-2984152-B2 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2022-01-05 — — EP disclosed
EP-2627730-B1 FORMULATIONS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2020-05-06 — — EP disclosed
US-10636990-B2 Organic electroluminescence device MERCK PATENT GMBH (DE) 2020-04-28 — — US disclosed
EP-2748878-B1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2020-04-01 — — EP disclosed
EP-2371016-B1 ORGANIC LIGHT EMITTING EVICES COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2019-08-07 — — EP disclosed
EP-3457450-A1 ORGANIC ELECTROLUMINESCENT DEVICE Merck Patent GmbH (DE) 2019-03-20 — — EP disclosed
EP-2984152-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2018-04-25 — — EP disclosed
US-20170309855-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2017-10-26 — — US disclosed
US-20170309855-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2017-10-26 — — US disclosed
US-8679647-B2 Organic electroluminescent device comprising triazine derivatives MERCK PATENT GMBH (DE) 2014-03-25 — — US disclosed
US-20130200357-A1 FORMULATIONS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-08-08 — — US disclosed
US-20130200357-A1 FORMULATIONS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-08-08 — — US disclosed
US-20130049579-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-02-28 — — US disclosed
US-20130049579-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-02-28 — — US disclosed
US-20110284831-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-24 — — US disclosed
US-20110284831-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-24 — — US disclosed
WO-2011141109-A1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-11-17 — — WO disclosed
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2011-04-28 — — US disclosed
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2011-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES KCNJ2, IKZF2, TERT L3MBTL1 2736/4885MEN1 4210/4885KMT2A 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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