Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12134160 | 0.94 | MAOA (0.32) | MAOA | |
| SCHEMBL12134144 | 0.94 | MAOA (0.31) | MAOA | |
| SCHEMBL12134159 | 0.88 | MAOA (0.32) | MAOA | |
| SCHEMBL12134138 | 0.86 | RORC (0.33) | — | |
| SCHEMBL12134169 | 0.85 | — | — | |
| SCHEMBL12134178 | 0.84 | — | — | |
| SCHEMBL12134173 | 0.83 | — | — | |
| SCHEMBL10207858 | 0.83 | MAOA (0.30) | MAOA | |
| SCHEMBL10079447 | 0.82 | MAPT (0.33) | MAOA | |
| SCHEMBL15215672 | 0.81 | RORC (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536351-B2 | 2-aryl-5-heterocyclyl-cyclohexane-1,3,dione compounds and their use as herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-17 | — | — | US | disclosed |
| US-8536351-B2 | 2-aryl-5-heterocyclyl-cyclohexane-1,3,dione compounds and their use as herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-17 | — | — | US | disclosed |
| US-20110281930-A1 | Use of 2-Aryl-5-heterocyclyl-cyclohexane-1,3-dione Compounds as Insecticides, Acaricides, and/ or Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-11-17 | — | — | US | disclosed |
| US-20110281930-A1 | Use of 2-Aryl-5-heterocyclyl-cyclohexane-1,3-dione Compounds as Insecticides, Acaricides, and/ or Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-11-17 | — | — | US | disclosed |
| EP-2134699-B1 | 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-1,3-DIONE COMPOUNDS AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010081687-A1 | USE OF 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-L,3-DIONE COMPOUNDS AS INSECTICIDES, ACARICIDES AND / OR FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | WO | disclosed |
| US-20100113270-A1 | 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-1,3,DIONE COMPOUNDS AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-20100113270-A1 | 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-1,3,DIONE COMPOUNDS AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2008110307-A1 | 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-1,3-DIONE COMPOUNDS AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113270-A1 | 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-1,3,DIONE COMPOUNDS AND THEIR USE AS HERBICIDES | C3AR1, C5, C9 | MAOA 3174/4885 |
| US-20110281930-A1 | Use of 2-Aryl-5-heterocyclyl-cyclohexane-1,3-dione Compounds as Insecticides, Acaricides, and/ or Fungicides | DDT, CYP1B1, CYP1A1 | MAOA 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.