SCHEMBL12134161

SCHEMBL12134161

CCc1cc(C)cc(CC)c1C1=C(O)CC(C2CCCSC2)CC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12134163 0.95
SCHEMBL12134162 0.87 HPGD (0.32)
SCHEMBL12134169 0.86
SCHEMBL12134168 0.81 MAOA (0.30)
SCHEMBL10079451 0.79
SCHEMBL12134136 0.79 MAOA (0.32)
SCHEMBL12134177 0.79
SCHEMBL12134180 0.78
SCHEMBL12134178 0.78
SCHEMBL12134144 0.78 MAOA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8536351-B2 2-aryl-5-heterocyclyl-cyclohexane-1,3,dione compounds and their use as herbicides SYNGENTA CROP PROTECTION LLC (US) 2013-09-17 US disclosed
US-8536351-B2 2-aryl-5-heterocyclyl-cyclohexane-1,3,dione compounds and their use as herbicides SYNGENTA CROP PROTECTION LLC (US) 2013-09-17 US disclosed
US-20110281930-A1 Use of 2-Aryl-5-heterocyclyl-cyclohexane-1,3-dione Compounds as Insecticides, Acaricides, and/ or Fungicides BAYER CROPSCIENCE AG (DE) 2011-11-17 US disclosed
US-20110281930-A1 Use of 2-Aryl-5-heterocyclyl-cyclohexane-1,3-dione Compounds as Insecticides, Acaricides, and/ or Fungicides BAYER CROPSCIENCE AG (DE) 2011-11-17 US disclosed
EP-2134699-B1 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-1,3-DIONE COMPOUNDS AND THEIR USE AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-05-11 EP disclosed
WO-2010081687-A1 USE OF 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-L,3-DIONE COMPOUNDS AS INSECTICIDES, ACARICIDES AND / OR FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-07-22 WO disclosed
US-20100113270-A1 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-1,3,DIONE COMPOUNDS AND THEIR USE AS HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-05-06 US disclosed
US-20100113270-A1 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-1,3,DIONE COMPOUNDS AND THEIR USE AS HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-05-06 US disclosed
WO-2008110307-A1 2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-1,3-DIONE COMPOUNDS AND THEIR USE AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-09-18 WO disclosed