Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780606 | 0.89 | FAAH (0.58) | GPR84FFAR1FFAR4FAAHTSHR | |
| SCHEMBL14168783 | 0.89 | FAAH (0.58) | GPR84FFAR1FFAR4FAAHTSHR | |
| SCHEMBL10777713 | 0.86 | FAAH (0.54) | GPR84FFAR1FFAR4FAAHKDM4E | |
| SCHEMBL25212694 | 0.83 | GPR84 (0.63) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL19066840 | 0.83 | GPR84 (0.63) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL533292 | 0.83 | GPR84 (0.63) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL25428960 | 0.83 | GPR84 (0.63) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL25432514 | 0.83 | GPR84 (0.63) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL2435216 | 0.83 | GPR84 (0.63) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL28466238 | 0.81 | FAAH (0.52) | GPR84FFAR1FFAR4FAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063249-B1 | Substituted triphenyl butenes | OLEMA PHARMACEUTICALS, INC. (US) | 2011-11-22 | — | — | US | disclosed |