SCHEMBL121365

SCHEMBL121365

COc1cccc(OC(CCCO)C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.53
LMNA P02545 1/20 0.49
PPARG P37231 8/20 0.48
ALOX5 P09917 2/20 0.48
PTGES O14684 1/20 0.48
PPARA Q07869 7/20 0.48
TSHR P16473 2/20 0.46
MAPK1 P28482 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MTNR1A P48039 5/20 0.46
MTNR1B P49286 5/20 0.46
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7142498 0.91 LMNA (0.51) FOLH1LMNAPPARGALOX5PTGES
SCHEMBL1565567 0.88 PPARG (0.61) FOLH1LMNAPPARGALOX5PTGES
SCHEMBL9092823 0.86 PPARG (0.55) FOLH1LMNAPPARGALOX5PTGES
SCHEMBL6393068 0.85 FOLH1 (0.41) FOLH1PPARGALOX5PTGESPPARA
SCHEMBL30475592 0.81 SMN1; SMN2 (0.59) LMNAPPARGPPARATSHRMAPK1
Aminodiphenylmethane SCHEMBL6631422 0.81 MTNR1A (0.45) FOLH1LMNAPPARGPPARAL3MBTL1
SCHEMBL5718636 0.78 KMT2A (0.55) LMNAPPARGALOX5PTGESPPARA
SCHEMBL1566435 0.77 PPARG (0.61) FOLH1PPARGALOX5PTGESPPARA
SCHEMBL5053288 0.76 FOLH1 (0.59) FOLH1PPARGALOX5PTGESPPARA
SCHEMBL940490 0.74 PPARG (0.58) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104619717-B The synthesis of β-corner simulation peptide cyclic compound 米梅奥亨制药公司 2019-04-02 CN claimed
CN-104619717-A Synthesis of beta-turn peptidomimetic cyclic compounds MIMETOGEN PHARMACEUTICALS INC 2015-05-13 CN claimed
US-7166696-B2 Solid phase synthesis supports and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-01-23 US claimed
US-20040265899-A1 Solid phase synthesis supports and methods 3M INNOVATIVE PROPERTIES COMPANY 2004-12-30 US claimed
US-6787635-B2 azlactone-functionalized support such as a crosslinked polymer containing an alkenyl azlactone; use making combinatorial libraries 3M INNOVATIVE PROPERTIES COMPANY 2004-09-07 US claimed
EP-1373167-A2 SOLID PHASE SYNTHESIS SUPPORTS AND METHODS 3M Innovative Properties Company (US) 2004-01-02 EP claimed
US-20020173051-A1 Solid phase synthesis supports and methods 3M INNOVATIVE PROPERTIES COMPANY 2002-11-21 US claimed
WO-2002081078-A2 SOLID PHASE SYNTHESIS SUPPORTS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-10-17 WO claimed
EP-4707386-A1 ARTIFICIAL VIRUS CAPSID AGC INC. (JP) 2026-03-11 EP disclosed
US-20260049107-A1 ARTIFICIAL VIRAL CAPSID AGC Inc. (JP) 2026-02-19 US disclosed
EP-4685154-A1 POLYPEPTIDE DERIVED FROM TRIDEGIN Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2026-01-28 EP disclosed
WO-2024228371-A1 ARTIFICIAL VIRUS CAPSID AGC株式会社 2024-11-07 WO disclosed
US-20240287131-A1 PEPTIDE AGC Inc. (JP) 2024-08-29 US disclosed
EP-4406961-A1 PEPTIDE AGC INC. (JP) 2024-07-31 EP disclosed
US-5891737-A ORTHOGONALLY PROTECTED TRIFUNCTIONAL SCAFFOLDS FOR SOLID PHASE SYNTHESIS OF PEPTIDOMIMETIC COMBINATORIAL LIBRARY ZYMOGENETICS, INC. (US) 1999-04-06 US disclosed
EP-0788370-A4 CYCLIC SEMI-RANDOM PEPTIDE LIBRARIES SMITHKLINE BEECHAM CORP (US) 1998-07-08 EP disclosed
EP-0788370-A1 CYCLIC SEMI-RANDOM PEPTIDE LIBRARIES SMITHKLINE BEECHAM CORPORATION (US) 1997-08-13 EP disclosed
US-5646285-A ORTHOGONALLY PROTECTED COMPOUNDS ZYMOGENETICS, INC. (US) 1997-07-08 US disclosed
WO-1996040732-A1 COMBINATORIAL NON-PEPTIDE LIBRARIES ZYMOGENETICS, INC. (US) 1996-12-19 WO disclosed
WO-1995001800-A1 CYCLIC SEMI-RANDOM PEPTIDE LIBRARIES SMITHKLINE BEECHAM CORPORATION (US) 1995-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287131-A1 PEPTIDE SSTR5, SSTR4, NGLY1 FOLH1 920/4885LMNA 4668/4885PPARG 4483/4885
US-20260049107-A1 ARTIFICIAL VIRAL CAPSID ZC3HAV1L, ZFR, SLC39A11 FOLH1 3225/4885LMNA 3737/4885PPARG 3162/4885
US-20020173051-A1 Solid phase synthesis supports and methods FES, LSS, CCNK FOLH1 4157/4885LMNA 1506/4885PPARG 4313/4885
US-20040265899-A1 Solid phase synthesis supports and methods FES, LSS, CCNK FOLH1 4157/4885LMNA 1506/4885PPARG 4313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.