Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | CDC42 | P60953 | 1/20 | 0.37 |
| ▸ | RAC1 | P63000 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144537 | 0.98 | PTGS2 (0.43) | PTGS2MTNR1AMTNR1BTDP1L3MBTL1 | |
| SCHEMBL13199789 | 0.94 | MTNR1A (0.41) | PTGS2MTNR1AMTNR1BTDP1L3MBTL1 | |
| SCHEMBL12136650 | 0.92 | MTNR1A (0.37) | PTGS2MTNR1AMTNR1BTDP1L3MBTL1 | |
| SCHEMBL10144533 | 0.91 | MTNR1A (0.39) | PTGS2MTNR1AMTNR1BTDP1L3MBTL1 | |
| SCHEMBL12136840 | 0.90 | PTGS2 (0.41) | PTGS2MTNR1AMTNR1BTDP1L3MBTL1 | |
| SCHEMBL13206420 | 0.87 | PTGS2 (0.39) | PTGS2MTNR1AMTNR1BTDP1L3MBTL1 | |
| SCHEMBL13206077 | 0.86 | PTGS2 (0.40) | PTGS2MTNR1AMTNR1BTDP1L3MBTL1 | |
| SCHEMBL10144564 | 0.85 | PTGS2 (0.41) | PTGS2MTNR1AMTNR1BTDP1L3MBTL1 | |
| SCHEMBL12135490 | 0.85 | PTGS2 (0.41) | PTGS2MTNR1AMTNR1BTDP1L3MBTL1 | |
| SCHEMBL10121564 | 0.85 | TDP1 (0.44) | PTGS2TDP1L3MBTL1PTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8062653-B2 | Controlled release of nitric oxide and drugs from functionalized macromers and oligomers | BEZWADA BIOMEDICAL, LLC (US) | 2011-11-22 | — | — | US | disclosed |