Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12138094 | 0.91 | MTOR (0.45) | MTORPIK3CA | |
| SCHEMBL12137913 | 0.90 | MTOR (0.44) | MTORPIK3CA | |
| SCHEMBL12138102 | 0.89 | MTOR (0.47) | MTORPIK3CA | |
| SCHEMBL12137504 | 0.88 | MTOR (0.49) | MTORPIK3CA | |
| SCHEMBL12137743 | 0.88 | MTOR (0.47) | MTORPIK3CA | |
| SCHEMBL6892332 | 0.87 | PIK3CA (0.59) | MTORPIK3CA | |
| SCHEMBL1357882 | 0.84 | MTOR (0.66) | MTORPIK3CA | |
| SCHEMBL12138100 | 0.83 | DHFR (0.54) | MTORPIK3CA | |
| SCHEMBL7873065 | 0.83 | MTOR (0.58) | MTOR | |
| SCHEMBL12137700 | 0.80 | PIK3CA (0.45) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281838-A1 | 5-ALKYNYL-PYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-17 | — | — | US | disclosed |
| WO-2010012740-A1 | 5-ALKYNYL-PYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281838-A1 | 5-ALKYNYL-PYRIMIDINES | MKI67, CCNA1, CCNT1 | MTOR 1488/4885PIK3CA 1567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.