SCHEMBL121394

SCHEMBL121394

CCCCCCCCCCCCN1CC(C(=O)O)CC1=O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.54
MEN1 O00255 1/20 0.51
CYP2C19 P33261 1/20 0.51
KMT2A Q03164 1/20 0.51
HTT P42858 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
GBA1 P04062 1/20 0.47
MAPT P10636 1/20 0.46
ALDH1A1 P00352 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14477978 1.00 POLB (0.56) POLBSMN1; SMN2L3MBTL1MEN1CYP2C19
SCHEMBL119623 1.00 POLB (0.56) POLBSMN1; SMN2L3MBTL1MEN1CYP2C19
SCHEMBL1283867 1.00 POLB (0.56) POLBSMN1; SMN2L3MBTL1MEN1CYP2C19
SCHEMBL8076306 1.00 POLB (0.56) POLBSMN1; SMN2L3MBTL1MEN1CYP2C19
SCHEMBL14477954 1.00 POLB (0.56) POLBSMN1; SMN2L3MBTL1MEN1CYP2C19
SCHEMBL15082405 1.00 POLB (0.56) POLBSMN1; SMN2L3MBTL1MEN1CYP2C19
SCHEMBL8084202 1.00 POLB (0.56) POLBSMN1; SMN2L3MBTL1MEN1CYP2C19
SCHEMBL2890516 1.00 POLB (0.56) POLBSMN1; SMN2L3MBTL1MEN1CYP2C19
SCHEMBL8084223 1.00 POLB (0.56) POLBSMN1; SMN2L3MBTL1MEN1CYP2C19
SCHEMBL14477956 1.00 POLB (0.56) POLBSMN1; SMN2L3MBTL1MEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3193849-A1 OPIPRAMOL PATCH Neuroderm, Ltd. (IL) 2017-07-26 EP claimed
WO-2016042413-A1 OPIPRAMOL PATCH NEURODERM, LTD. (IL) 2016-03-24 WO claimed
US-20120202891-A1 Cannabinoid-Containing Compositions and Methods for Their Use UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2012-08-09 US claimed
EP-2424568-A1 CANNABINOID-CONTAINING COMPOSITIONS AND METHODS FOR THEIR USE University Of Kentucky Research Foundation (US) 2012-03-07 EP claimed
US-7879344-B2 contains antiitch agent; for use in wipes and absorbent articles, and transdermal patches KIMBERLY-CLARK WORLDWIDE, INC. (US) 2011-02-01 US claimed
WO-2010126501-A1 CANNABINOID-CONTAINING COMPOSITIONS AND METHODS FOR THEIR USE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2010-11-04 WO claimed
EP-2040693-A2 TRANSDERMAL DELIVERY OF OLEOCANTHAL FOR RELIEF OF INFLAMMATION Kimberly-Clark Worldwide, Inc. (US) 2009-04-01 EP claimed
WO-2008001240-A2 TRANSDERMAL DELIVERY OF OLEOCANTHAL FOR RELIEF OF INFLAMMATION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-01-03 WO claimed
US-20080003273-A1 Transdermal Delivery of Oleocanthal for Relief of Inflammation KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-01-03 US claimed
US-7137975-B2 Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent ACIONT, INC. (US) 2006-11-21 US claimed
US-20020161323-A1 Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent ACIONT INC. 2002-10-31 US claimed
EP-0813879-B1 Drug administration composition for iontophoresis HISAMITSU PHARMACEUTICAL CO (JP) 2002-10-30 EP claimed
JP-2000512663-A 2000-09-26 JP claimed
EP-1003469-A2 FRAGRANCE PRECURSORS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 2000-05-31 EP claimed
WO-1997030687-A2 FRAGRANCE PRECURSORS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-08-28 WO claimed
US-12636309-B2 Storage stable formulations of sulfated glycosaminoglycans and fragments derived therefrom for the treatment of pain and other medical conditions ADORA ANIMAL HEALTH CORPORATION (US) 2026-05-26 US disclosed
US-12636308-B2 Storage stable formulations of sulfated glycosaminoglycans and fragments derived therefrom for the treatment of pain and other medical conditions ADORA ANIMAL HEALTH CORPORATION (US) 2026-05-26 US disclosed
CN-1171269-A Drug administration composition for iontophoresis HISAMITSU PHARMACEUTICAL CO (JP) 1998-01-28 CN disclosed
EP-0813887-A2 A device structure for iontophoresis HISAMITSU PHARMACEUTICAL CO. INC. (JP) 1997-12-29 EP disclosed
EP-0813879-A2 Drug administration composition for iontophoresis HISAMITSU PHARMACEUTICAL CO. INC. (JP) 1997-12-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080003273-A1 Transdermal Delivery of Oleocanthal for Relief of Inflammation OXER1, OSBP, OXGR1 POLB 2495/4885SMN1; SMN2 4130/4885L3MBTL1 4617/4885
US-12636308-B2 Storage stable formulations of sulfated glycosaminoglycans and fragments derived therefrom for the treatment of pain and other medical conditions FUT6, CD44, CSGALNACT1 POLB 3151/4885SMN1; SMN2 1287/4885L3MBTL1 4408/4885
US-12636309-B2 Storage stable formulations of sulfated glycosaminoglycans and fragments derived therefrom for the treatment of pain and other medical conditions CD44, FUT8, FUT6 POLB 3840/4885SMN1; SMN2 239/4885L3MBTL1 3320/4885
US-20120202891-A1 Cannabinoid-Containing Compositions and Methods for Their Use CNR2, CNR1, FAAH POLB 2397/4885SMN1; SMN2 2533/4885L3MBTL1 4725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.