Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13684369 | 0.86 | — | — | |
| SCHEMBL18568141 | 0.85 | — | — | |
| SCHEMBL6874072 | 0.85 | CA2 (0.33) | — | |
| SCHEMBL16349615 | 0.85 | — | — | |
| SCHEMBL904230 | 0.84 | CNR2 (0.31) | — | |
| SCHEMBL13684446 | 0.83 | CYP2C19 (0.34) | — | |
| SCHEMBL13684371 | 0.82 | EPHX1 (0.33) | — | |
| SCHEMBL16093490 | 0.81 | HTT (0.35) | — | |
| SCHEMBL12404656 | 0.80 | DPP4 (0.31) | — | |
| SCHEMBL6876386 | 0.80 | MME (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067379-B2 | Sulfur compounds as inhibitors of hepatitis C virus NS3 serine protease | SCHERING CORPORATION (US) | 2011-11-29 | — | — | US | disclosed |
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |