Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18567880 | 0.85 | — | — | |
| SCHEMBL8285874 | 0.83 | PPID (0.41) | — | |
| SCHEMBL16349615 | 0.82 | — | — | |
| SCHEMBL12140488 | 0.80 | GHSR (0.30) | — | |
| SCHEMBL16093490 | 0.79 | HTT (0.35) | — | |
| SCHEMBL6878976 | 0.79 | LMNA (0.38) | — | |
| SCHEMBL12404656 | 0.78 | DPP4 (0.31) | — | |
| SCHEMBL18568231 | 0.78 | FAP (0.39) | — | |
| SCHEMBL6874072 | 0.77 | CA2 (0.33) | — | |
| SCHEMBL10310655 | 0.77 | NPSR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459525-B1 | ENANTIO- AND STEREO-SPECIFIC SYNTHESES OF -AMINO- - HYDROXY AMIDES | MERCK SHARP & DOHME (US) | 2017-03-01 | — | — | EP | disclosed |
| WO-2011014494-A1 | ENANTIO- AND STEREO-SPECIFIC SYNTHESES OF β-AMINO-α- HYDROXY AMIDES | SCHERING CORPORATION (US) | 2011-02-03 | — | — | WO | disclosed |