Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112043 | 1.00 | EPHX1 (0.53) | EPHX1NAAAFAAHACHETSHR | |
| SCHEMBL111373 | 1.00 | EPHX1 (0.53) | EPHX1NAAAFAAHACHETSHR | |
| SCHEMBL113441 | 1.00 | EPHX1 (0.53) | EPHX1NAAAFAAHACHETSHR | |
| SCHEMBL121408 | 1.00 | EPHX1 (0.53) | EPHX1NAAAFAAHACHETSHR | |
| SCHEMBL111056 | 1.00 | EPHX1 (0.53) | EPHX1NAAAFAAHACHETSHR | |
| SCHEMBL109499 | 1.00 | EPHX1 (0.53) | EPHX1NAAAFAAHACHETSHR | |
| SCHEMBL121805 | 0.93 | ALDH1A1 (0.45) | EPHX1NAAAACHETSHRHCAR2 | |
| SCHEMBL121806 | 0.93 | ALDH1A1 (0.45) | EPHX1NAAAACHETSHRHCAR2 | |
| SCHEMBL122567 | 0.93 | ALDH1A1 (0.45) | EPHX1NAAAACHETSHRHCAR2 | |
| SCHEMBL113196 | 0.85 | KDM4E (0.35) | EPHX1ACHETSHRHCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424499-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | Abbott Laboratories (US) | 2012-03-07 | — | — | EP | claimed |
| WO-2010127193-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | ABBOTT LABORATORIES (US) | 2010-11-04 | — | — | WO | claimed |