Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 7/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121805 | 1.00 | ALDH1A1 (0.45) | ALDH1A1EPHX1ATMTSHRHPGD | |
| SCHEMBL122567 | 1.00 | ALDH1A1 (0.45) | ALDH1A1EPHX1ATMTSHRHPGD | |
| SCHEMBL121407 | 0.93 | EPHX1 (0.53) | ALDH1A1EPHX1TSHRACHEHCAR2 | |
| SCHEMBL112043 | 0.93 | EPHX1 (0.53) | ALDH1A1EPHX1TSHRACHEHCAR2 | |
| SCHEMBL113441 | 0.93 | EPHX1 (0.53) | ALDH1A1EPHX1TSHRACHEHCAR2 | |
| SCHEMBL121408 | 0.93 | EPHX1 (0.53) | ALDH1A1EPHX1TSHRACHEHCAR2 | |
| SCHEMBL111056 | 0.93 | EPHX1 (0.53) | ALDH1A1EPHX1TSHRACHEHCAR2 | |
| SCHEMBL111373 | 0.93 | EPHX1 (0.53) | ALDH1A1EPHX1TSHRACHEHCAR2 | |
| SCHEMBL109499 | 0.93 | EPHX1 (0.53) | ALDH1A1EPHX1TSHRACHEHCAR2 | |
| SCHEMBL113196 | 0.89 | KDM4E (0.35) | ALDH1A1EPHX1TSHRACHEHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424499-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | Abbott Laboratories (US) | 2012-03-07 | — | — | EP | claimed |
| WO-2010127193-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | ABBOTT LABORATORIES (US) | 2010-11-04 | — | — | WO | claimed |