Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.63 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.59 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.40 |
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5677296 | 0.83 | CXCR4 (0.79) | CXCR4APOBEC3AAPOBEC3GWDR5ADRA2A | |
| SCHEMBL2951088 | 0.83 | CXCR4 (0.61) | CXCR4APOBEC3AAPOBEC3GWDR5ADRA2A | |
| Bromide SCHEMBL8624628 | 0.81 | CXCR4 (0.76) | CXCR4APOBEC3AAPOBEC3GWDR5ADRA2A | |
| SCHEMBL29025292 | 0.76 | APOBEC3A (0.54) | CXCR4APOBEC3AAPOBEC3GWDR5ADRA2A | |
| SCHEMBL13512431 | 0.76 | — | — | |
| SCHEMBL12966337 | 0.76 | — | — | |
| SCHEMBL12132035 | 0.74 | CXCR4 (0.66) | CXCR4APOBEC3AAPOBEC3GWDR5ADRA2A | |
| SCHEMBL6301909 | 0.73 | CXCR4 (0.75) | CXCR4APOBEC3AAPOBEC3GWDR5ADRA2A | |
| SCHEMBL13509984 | 0.73 | CXCR4 (0.63) | CXCR4APOBEC3AAPOBEC3GWDR5ADRA2A | |
| SCHEMBL2492454 | 0.73 | CXCR4 (0.75) | CXCR4APOBEC3AAPOBEC3GWDR5ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8646616-B2 | Composite membrane with coating comprising polyalkylene oxide and imidazol compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-02-11 | — | — | US | disclosed |
| US-20110284454-A1 | COMPOSITE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND IMIDAZOL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-24 | — | — | US | disclosed |